Evidence map›Paper›PMID 25802973›Full record

ArticleToxins2015

Further evidence for staphylococcal food poisoning outbreaks caused by egc-encoded enterotoxins.

Sophia Johler, Petra Giannini, Marco Jermini, Jörg Hummerjohann, Andreas Baumgartner, Roger Stephan

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 123 citations in OpenAlex.

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  3. Clarifying the Dual Role ofFoods (Basel, Switzerland) · 2025
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  9. Molecular characterization and antibiotic resistance ofFood science and biotechnology · 2024
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  10. Article
  11. High toxinogenic potential ofFrontiers in veterinary science · 2024
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  12. Article
  13. Article
  14. Article
  15. Article
  16. Genomic characterization of Staphylococcus aureus from Canastra Minas Artisanal Cheeses.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  17. Genomic characterization of Staphylococcus aureus from Canastra Minas Artisanal Cheeses.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Sophia JohlerInstitute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland. sophia.johler@uzh.ch.
Petra GianniniCantonal Laboratory, Via Mirasole 22, 6500 Bellinzona, Switzerland. petra.giannini@ti.ch.
Marco JerminiCantonal Laboratory, Via Mirasole 22, 6500 Bellinzona, Switzerland. dss-lc@ti.ch.
Jörg HummerjohannAgroscope, Institute for Food Sciences, Schwarzenburgerstrasse 161, 3003 Bern, Switzerland. joerg.hummerjohann@agroscope.admin.ch.
Andreas BaumgartnerFederal Food Safety and Veterinary Office, Schwarzenburgerstrasse 155, 3003 Bern, Switzerland. andreas.baumgartner@blv.admin.ch.
Roger StephanInstitute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland. ils@fsafety.uzh.ch.
Repubblica e Cantone Ticino · CHUniversity of Zurich · CHAgroscope · CHFederal Food Safety and Veterinary Office · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcal food poisoning represents the most prevalent foodborne intoxication worldwide. It is caused by oral intake of enterotoxins preformed by Staphylococcus aureus in food. The relevance of newly described enterotoxins in outbreaks of staphylococcal food poisoning is controversially discussed. Although the staphylococcal enterotoxins SEG, SEI, SEM, SEN, and SEO elicit emesis in a monkey feeding assay, there has been no conclusive proof of their emetic activity in humans. In this study, we provide further evidence suggesting that one of these enterotoxins or a combination of SEG, SEI, SEM, SEN, and SEO cause staphylococcal food poisoning. We investigated two outbreaks registered with the Swiss Federal Office of Public Health, in which only Staphylococcus aureus strains harboring the egc cluster, including seg, sei, sem, sen, and seo linked to typical signs of staphylococcal food poisoning were isolated. The outbreaks were caused by consumption of raw goat cheese and semi-hard goat cheese, and were linked to strains assigned to CC45 (agr type I) and CC9 (agr type II), respectively. These outbreaks provide further evidence that newly-described staphylococcal enterotoxins are likely to cause staphylococcal food poisoning in humans.

Indexed as

Disease OutbreaksAnimalsCheeseDNA, BacterialEnterotoxinsFood ContaminationFood MicrobiologyGenotyping TechniquesGoatsHumansMultigene FamilyOligonucleotide Array Sequence AnalysisRisk FactorsStaphylococcal Food PoisoningStaphylococcus aureusDNA, BacterialEnterotoxins

Identifiers

PMID25802973
PMCPMC4379538
OpenAlexW1969994874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.