Evidence map›Paper›PMID 25782136›Full record

Trial reportMedical science monitor : international medical journal of experimental and clinical research2015

Preoperative cognitive intervention reduces cognitive dysfunction in elderly patients after gastrointestinal surgery: a randomized controlled trial.

Amin J Saleh, Guan-Xiu Tang, Sally M Hadi, Liao Yan, Ming-Hua Chen, Kai-Ming Duan, Jianbin Tong, Wen Ouyang

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medical science monitor : international medical journal of experimental and clinical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03620968 ("Implementation of a Cognitive Training Program in the Elderly to Reduce the Risk of Postoperative Cognitive Dysfunction in Elective Non-cardiac Surgery "), which is not on this map. Cited by 43 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03620968 nacompletednot on this mapstarted 2018, after this paper: background citation

"Implementation of a Cognitive Training Program in the Elderly to Reduce the Risk of Postoperative Cognitive Dysfunction in Elective Non-cardiac Surgery "

TypeinterventionalSponsorCentro Medico TeknonRan2018 to 2022Enrolled225ConditionsPostoperative Cognitive DysfunctionArmscognitive training
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  20. The impact of geriatric-specific variables on long-term outcomes in patients with hepatopancreatobiliary and colorectal cancer selected for resection.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · 2024
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amin J SalehDepartment of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).
Guan-Xiu TangDepartment of Nurse, Third Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).
Sally M HadiDepartment of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).
Liao YanDepartment of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).
Ming-Hua ChenDepartment of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).
Kai-Ming DuanDepartment of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).
Jianbin TongDepartment of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).
Wen OuyangDepartment of Anesthesiology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreoperative conditions may play a significant role in postoperative cognitive dysfunction (POCD) development in elderly patients. We aimed to investigate whether preoperative cognitive training could lower the incidence of POCD one week after surgery. MATERIAL AND

methodsA total of 141 ASA I-III elderly patients who underwent gastrointestinal surgery were enrolled into the study. Patients were randomized into either the Intervention group (69 analyzed) or the Control group (72 analyzed). Patients in the intervention group were instructed and trained in a cognition mnemonic skill for a total of three 1-hour sessions with the method of loci (MoL). Controls did not receive any cognitive training during hospitalization. All patients were tested using neuropsychological battery tests (NPTs) on admission and one week after surgery.

resultsThe incidence of POCD in the intervention group (15.9%) was significantly lower than in the controls (36.1%) (P<0.05). Patients' performance in Brief Visuospatial Memory Test-Revised and Symbol-Digit Modalities Test were improved by the cognitive training. Increasing age, longer length of anesthesia and surgery, and lack of cognitive training were associated with a significantly higher risk of POCD (P<0.05).

conclusionsCognitive training with MoL can reduce the decline of early postoperative cognitive function in elderly patients undergoing major gastrointestinal surgery.

Indexed as

CognitionPreoperative CareAgedCognition DisordersDigestive System Surgical ProceduresFemaleFollow-Up StudiesHumansMalePostoperative CarePostoperative ComplicationsRisk Factors

Identifiers

PMID25782136
PMCPMC4373157

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.