Evidence map›Paper›PMID 25516539›Full record

ReviewBMJ (Clinical research ed.)2014

SearCh for humourIstic and Extravagant acroNyms and Thoroughly Inappropriate names For Important Clinical trials (SCIENTIFIC): qualitative and quantitative systematic study.

Anton Pottegård, Maija Bruun Haastrup, Tore Bjerregaard Stage, Morten Rix Hansen, Kasper Søltoft Larsen, Peter Martin Meegaard, Line Haugaard Vrdlovec Meegaard, Henrik Horneberg, Charlotte Gils, Dorthe Dideriksen and 4 more

Abstract readReview
In one paragraph

Review in BMJ (Clinical research ed.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. CASE (Philadelphia, Pa.) · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Anton PottegårdClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark apottegaard@health.sdu.dk.
Maija Bruun HaastrupDepartment of Clinical Chemistry and Pharmacology, Odense University Hospital, Odense C, Denmark.
Tore Bjerregaard StageClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark.
Morten Rix HansenClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark.
Kasper Søltoft LarsenClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark.
Peter Martin MeegaardCapital Region Pharmacy, Clinical pharmaceutical Services, Rigshospitalet, Copenhagen, Denmark.
Line Haugaard Vrdlovec MeegaardCapital Region Pharmacy, Clinical pharmaceutical Services, Nordsjællands Hospital, Hillerød, Denmark.
Henrik HornebergClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark.
Charlotte GilsDepartment of Clinical Chemistry and Pharmacology, Odense University Hospital, Odense C, Denmark.
Dorthe DideriksenDepartment of Clinical Chemistry and Pharmacology, Odense University Hospital, Odense C, Denmark.
Lise AagaardClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark.
Anna Birna AlmarsdottirClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark Department of Clinical Chemistry and Pharmacology, Odense University Hospital, Odense C, Denmark.
Jesper HallasClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark Department of Clinical Chemistry and Pharmacology, Odense University Hospital, Odense C, Denmark.
Per DamkierClinical Pharmacology, Institute of Public Health, University of Southern Denmark, DK-5000 Odense C, Denmark Department of Clinical Chemistry and Pharmacology, Odense University Hospital, Odense C, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the development of acronym use across five major medical specialties and to evaluate the technical and aesthetic quality of the acronyms.

designAcronyms obtained through a literature search of Pubmed.gov followed by a standardised assessment of acronym quality (BEAUTY and CHEATING criteria).

participantsRandomised controlled trials within psychiatry, rheumatology, pulmonary medicine, endocrinology, and cardiology published between 2000 and 2012.

main outcome measuresPrevalence proportion of acronyms and composite quality score for acronyms over time.

results14,965 publications were identified, of which 18.3% (n=2737) contained an acronym in the title. Acronym use was more common among cardiological studies than among the other four medical specialties (40% v 8-15% in 2012, P<0.001). Except for within cardiology, the prevalence of acronyms increased over time, with the average prevalence proportion among the remaining four specialties increasing from 4.0% to 12.4% from 2000 to 2012 (P<0.001). The median combined acronym quality score decreased significantly over the study period (P<0.001), from a median 9.25 in 2000 to 5.50 in 2012.

conclusionFrom 2000 to 2012 the prevalence of acronyms in trial reports increased, coinciding with a substantial decrease in the technical and aesthetic quality of the acronyms. Strict enforcement of current guidelines on acronym construction by journal editors is necessary to ensure the proper use of acronyms in the future.

Indexed as

Abbreviations as TopicClinical Trials as TopicTerminology as TopicHumansNamesPeriodicals as TopicPubMedUnified Medical Language System

Identifiers

PMID25516539
PMCPMC4267482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.