ReviewClinical reviews in allergy & immunology2015
Shellfish Allergy: a Comprehensive Review.
Review in Clinical reviews in allergy & immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 104 citations in OpenAlex.
- Crustacean and Mollusc Shell Proteins: Origin, Structure, and Functionality.Journal of food science · 2026Review
- Valorisation of Protein from Underutilised Harbour Crab (Foods (Basel, Switzerland) · 2025Article
- Review
- Review
- [Novel foods-What must be considered?]Dermatologie (Heidelberg, Germany) · 2025Review
- Clinical Relevance of Immunologic Diagnosis of Shrimp Allergy in Adults.Allergy, asthma & immunology research · 2025Article
- Research Progress on Shrimp Allergens and Allergenicity Reduction Methods.Foods (Basel, Switzerland) · 2025Review
- A Double-Gene Metabarcoding Approach for the Authentication of Shrimp Surimi-Based Products.Genes · 2025Article
- Recent Advances of Processing and Detection Techniques on Crustacean Allergens: A Review.Foods (Basel, Switzerland) · 2025Review
- A deep dive into shrimp allergy: clinical spectrum of shrimp allergy in a Tunisian pilot study.Frontiers in allergy · 2025Article
- Astrocytic gatekeeping of neural circuitry and synaptic balance in an autism mouse model: mechanistic insights beyondFrontiers in cell and developmental biology · 2025Article
- A comprehensive review of arginine kinase proteins: What we need to know?Biochemistry and biophysics reports · 2024Review
- IgE Mediated Shellfish Allergy in Children-A Review.Nutrients · 2023Review
- Development of gastro-food allergy model in shrimp allergen extract-induced sensitized mice promotes mast cell degranulation.Journal of public health in Africa · 2023Article
- IgE reactivity patterns in Asian and central European cockroach-sensitized patients reveal differences in primary sensitizing allergen sources.The journal of allergy and clinical immunology. Global · 2022Article
- Visual detection of tropomyosin, a major shrimp allergenic protein using gold nanoparticles (AuNPs)-assisted colorimetric aptasensor.Marine life science & technology · 2021Article
- Allergens from Edible Insects: Cross-reactivity and Effects of Processing.Current allergy and asthma reports · 2021Review
- IgE and IgG4 responses to shrimp allergen tropomyosin and its epitopes in patients from coastal areas of northern China.Molecular medicine reports · 2020Article
- House Dust Mite-Shrimp Allergen Interrelationships.Current allergy and asthma reports · 2020Review
- Occupational allergic contact urticaria to tropomyosin from squid.Allergologie select · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Shellfish allergy is of increasing concern, as its prevalence has risen in recent years. Many advances have been made in allergen characterization. B cell epitopes in the major allergen tropomyosin have been characterized. In addition to tropomyosin, arginine kinase, sarcoplasmic calcium-binding protein, and myosin light chain have recently been reported in shellfish. All are proteins that play a role in muscular contraction. Additional allergens such as hemocyanin have also been described. The effect of processing methods on these allergens has been studied, revealing thermal stability and resistance to peptic digestion in some cases. Modifications after Maillard reactions have also been addressed, although in some cases with conflicting results. In recent years, new hypoallergenic molecules have been developed, which constitute a new therapeutic approach to allergic disorders. A recombinant hypoallergenic tropomyosin has been developed, which opens a new avenue in the treatment of shellfish allergy. Cross-reactivity with species that are not closely related is common in shellfish-allergic patients, as many of shellfish allergens are widely distributed panallergens in invertebrates. Cross-reactivity with house dust mites is well known, but other species can also be involved in this phenomenon.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.