Evidence map›Paper›PMID 24564482›Full record

ArticleBMC bioinformatics2014

Toolboxes for a standardised and systematic study of glycans.

Matthew P Campbell, René Ranzinger, Thomas Lütteke, Julien Mariethoz, Catherine A Hayes, Jingyu Zhang, Yukie Akune, Kiyoko F Aoki-Kinoshita, David Damerell, Giorgio Carta and 7 more

Abstract read
In one paragraph

Article in BMC bioinformatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. An Interactive View of Glycosylation.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  2. Article
  3. Review
  4. glypy: An Open Source Glycoinformatics Library.Journal of proteome research · 2019
    Article
  5. Review
  6. Article
  7. Article
  8. SugarSketcher: Quick and Intuitive Online Glycan Drawing.Molecules (Basel, Switzerland) · 2018
    Article
  9. Glycomics@ExPASy: Bridging the Gap.Molecular & cellular proteomics : MCP · 2018
    Article
  10. Article
  11. Review
  12. Review
  13. Glycosaminoglycanomics: where we are.Glycoconjugate journal · 2017
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. GlycoRDF: an ontology to standardize glycomics data in RDF.Bioinformatics (Oxford, England) · 2015
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Matthew P Campbell
René Ranzinger
Thomas Lütteke
Julien Mariethoz
Catherine A Hayes
Jingyu Zhang
Yukie Akune
Kiyoko F Aoki-Kinoshita
David Damerell
Giorgio Carta
Will S York
Stuart M Haslam
Hisashi Narimatsu
Pauline M Rudd
Niclas G Karlsson
Nicolle H Packer
Frédérique Lisacek

Funding

TR&D1: Stem Cell and Induced Pluripotent Stem Cell Resources (Pages 116-134)P41GM103490 · NIGMS · UNIVERSITY OF GEORGIA · PI PIERCE, J. MICHAEL · 2012 to 2018
$13.7M
Biotechnology and Biological Sciences Research Council BB/F008309/1NIGMS NIH HHS 8P41GM103490NIGMS NIH HHS P41 GM103490
6 · The paper itself

Abstract

backgroundRecent progress in method development for characterising the branched structures of complex carbohydrates has now enabled higher throughput technology. Automation of structure analysis then calls for software development since adding meaning to large data collections in reasonable time requires corresponding bioinformatics methods and tools. Current glycobioinformatics resources do cover information on the structure and function of glycans, their interaction with proteins or their enzymatic synthesis. However, this information is partial, scattered and often difficult to find to for non-glycobiologists.

methodsFollowing our diagnosis of the causes of the slow development of glycobioinformatics, we review the "objective" difficulties encountered in defining adequate formats for representing complex entities and developing efficient analysis software.

resultsVarious solutions already implemented and strategies defined to bridge glycobiology with different fields and integrate the heterogeneous glyco-related information are presented.

conclusionsDespite the initial stage of our integrative efforts, this paper highlights the rapid expansion of glycomics, the validity of existing resources and the bright future of glycobioinformatics.

Indexed as

Carbohydrate SequenceGlycomicsInternetPolysaccharidesProteinsSoftwarePolysaccharidesProteins

Identifiers

PMID24564482
PMCPMC4016020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.