Evidence map›Paper›PMID 24239923›Full record

GuidelineJournal of the American College of Cardiology2014

2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.

Neil J Stone, Jennifer G Robinson, Alice H Lichtenstein, C Noel Bairey Merz, Conrad B Blum, Robert H Eckel, Anne C Goldberg, David Gordon, Daniel Levy, Donald M Lloyd-Jones and 7 more

Erratum issued 10 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Journal of the American College of Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 10 registered trials, which are not on this map. Cited by 1,788 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,788citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02740699 phase4terminatedstarted 2016, after this paper: background citation

CT COMPARE: CT Coronary Angiography to Measure Plaque Reduction

Ran2016Enrolled79Registered outcomes6Posted comparisons6ConditionsCardiovascular DiseaseArmsAtorvastatin, Cardiac Computed Tomography (CT), Cardiac Magnetic Resonance Image (MRI), Rosuvastatin
PMID 22883507PMID 23206978other papers from this trial
Open the trial in the graph
NCT03067844 phase3completedstarted 2017, after this paper: background citation

Effects of the PCSK9 Antibody AliroCuMab on Coronary Atherosclerosis in PatieNts With Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy And Optical Coherence Tomography Imaging Study

Ran2017Enrolled294Registered outcomes16Posted comparisons0ConditionsAtheroma; Myocardial, Coronary Circulation, Coronary VesselArmsAlirocumab
Open the trial in the graph
NCT03696940 phase3unknown statusstarted 2018, after this paper: background citation

Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina

Ran2018Enrolled120Registered outcomes6Posted comparisons0ConditionsCardiovascular Risk Factor, DyslipidemiasArmsAtorvastatin 10mg, L-Carnitine 500Mg Oral Tablet + Atorvastatin 10 mg
Open the trial in the graph
NCT06767774 phase4recruitingstarted 2025, after this paper: background citation

Comparison of Pitavastatin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus in Prediabetic Patients With Atherosclerotic Cardiovascular Disease

Ran2025Enrolled2,000Registered outcomes13Posted comparisons0ConditionsASCVD, Diabetes, StatinArmsCombination therapy, High intensity statin monotherapy
Open the trial in the graph
NCT03027336 phase2completednot on this mapstarted 2016, after this paper: background citation

Randomized Controlled Clinical Trial for Assessing Tolerability and Effectiveness of Formula Coleosoma 29 in Patients With Dyslipidemia

TypeinterventionalSponsorAzienda Ospedaliero-Universitaria di ParmaRan2016 to 2016Enrolled39ConditionsDyslipidemiasArmsColeosoma, Placebo
NCT03216057 nacompletednot on this map

Effect of Omega-3 Fatty Acids Supplementation on Hypertriglyceridemia in Pediatric Patients With Obesity. A Randomized, Double Blind, Placebo-controlled Clinical Trial.

TypeinterventionalSponsorHospital Infantil de Mexico Federico GomezRan2008 to 2016Enrolled168ConditionsHypertriglyceridemia, Pediatric ObesityArmsOmega-3 fatty acid 3 grams per day, Placebo
NCT04526457 nacompletednot on this map

Is Family Screening Improved by Genetic Testing of Familial Hypercholesterolemia

TypeinterventionalSponsorUniversity of PennsylvaniaRan2014 to 2017Enrolled240ConditionsHypercholesterolemia, FamilialArmsStandard of Care, Genetic Testing
NCT05072275 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prospective Electronic Polygenic Risk Study (PEPRS) - First Phase

TypeobservationalSponsorScripps Translational Science InstituteRan2023 to 2023Enrolled1,000ConditionsCoronary Artery Disease
NCT05175651 nanot yet recruitingnot on this mapstarted 2023, after this paper: background citation

Prospective Electronic Polygenic Risk Study - Second Phase

TypeinterventionalSponsorScripps Translational Science InstituteRan2023 to 2027Enrolled10,000ConditionsCoronary Artery Disease, GlaucomaArmsGenetic risk assessment
NCT05629767 terminatednot on this mapstarted 2022, after this paper: background citation

Tracking Lipid-Lowering Therapy Over One Year in Middle Eastern Patients With ASCVD. The Jordan LLA Tracking Study

Typeobservational_patient_registrySponsorJordan Collaborating Cardiology GroupRan2022 to 2024Enrolled1,000ConditionsDyslipidemias, Atherosclerotic Cardiovascular Disease
3 · Its place in the literature

Who cites it

1,788 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Article
  12. The Cog-Aging: a 15-year cohort study of cognition in Brazilian older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  13. Review
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

1,728 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Neil J Stone
Jennifer G Robinson
Alice H Lichtenstein
C Noel Bairey Merz
Conrad B Blum
Robert H Eckel
Anne C Goldberg
David Gordon
Daniel Levy
Donald M Lloyd-Jones
Patrick McBride
J Sanford Schwartz
Susan T Shero
Sidney C Smith
Karol Watson
Peter W F Wilson
American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAmerican Heart AssociationCardiologyCholesterol, HDLCholesterol, LDLCoronary Artery DiseaseHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaRisk AssessmentRisk FactorsRisk Reduction BehaviorSocieties, MedicalUnited StatesCholesterol, HDLCholesterol, LDLHydroxymethylglutaryl-CoA Reductase InhibitorsACC/AHA Practice Guidelinebiomarkers, pharmacologicalcardiovascular diseasecholesteroldiabetes mellitusdrug therapyhydroxymethylglutaryl-CoA reductase inhibitors/statinshypercholesterolemialipidspatient complianceprimary preventionrisk assessmentrisk reduction behaviorsecondary prevention

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 4 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.