ArticleHippocampus2013
Repetition related changes in activation and functional connectivity in hippocampus predict subsequent memory.
Article in Hippocampus, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- The human hippocampus can pattern separate memories by meaning.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Hippocampal connectivity predicting recognition and categorization abilities.Frontiers in cognition · 2026Article
- Insights on the neurocognitive mechanisms underlying hippocampus-dependent memory impairment in COVID-19.Scientific reports · 2025Article
- Hippocampal Functions Modulate Transfer-Appropriate Cortical Representations Supporting Subsequent Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Optimizing the mnemonic similarity task for efficient, widespread use.Frontiers in behavioral neuroscience · 2023Article
- Habituation during encoding: A new approach to the evaluation of memory deficits in schizophrenia.Schizophrenia research · 2020Article
- Left Inferior Frontal Gyrus Participates in Mediating the Renewal Effect Irrespective of Context Salience.Frontiers in behavioral neuroscience · 2020Article
- Multiple Exposures Enhance Both Item Memory and Contextual Memory Over Time.Frontiers in psychology · 2020Article
- Differential Functional Connectivity along the Long Axis of the Hippocampus Aligns with Differential Role in Memory Specificity and Generalization.Journal of cognitive neuroscience · 2019Article
- Mnemonic Similarity Task: A Tool for Assessing Hippocampal Integrity.Trends in cognitive sciences · 2019Review
- Effects of Repetition Learning on Associative Recognition Over Time: Role of the Hippocampus and Prefrontal Cortex.Frontiers in human neuroscience · 2018Article
- Parahippocampal Cortex Processes the Nonspatial Context of an Event.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Reactivation during encoding supports the later discrimination of similar episodic memories.Hippocampus · 2016Article
- fMRI exploration of pedagogical benefits of repeated testing: when more is not always better.Brain and behavior · 2016Article
- Detecting analogies unconsciously.Frontiers in behavioral neuroscience · 2014Article
- Article
- Neural correlates of retrieval-based memory enhancement: an fMRI study of the testing effect.Neuropsychologia · 2013Article
- Identical versus conceptual repetition FN400 and parietal old/new ERP components occur during encoding and predict subsequent memory.Brain research · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Using fMRI, this study examined the relationship between repetition-related changes in the medial temporal lobe (MTL) activation during encoding and subsequent memory for similarity of repetitions. During scanning, subjects classified pictures of objects as natural or man-made. Each object-type was judged twice with presentations of either identical pictures or pictures of different exemplars of the same object. After scanning, a surprise recognition test required subjects to decide whether a probe word corresponded to pictures judged previously. When a subject judged the word as "old," a second judgment was made concerning the physical similarity of the two pictures. Repetition related changes in MTL activation varied depending on whether or not subjects could correctly state that pictures were different. Moreover, psychophysiological interactions analyses showed that accuracy in recalling whether the two pictures were different was predicted by repetition-related changes in the functional connectivity of MTL with frontal regions. Specifically, correct recollection was predicted by increased connectivity between the left posterior hippocampus and the right inferior frontal gyrus, and also by decreased connectivity between the left posterior hippocampus and the left precentral gyrus on the second stimulus presentation. The opposite pattern was found for trials that were incorrectly judged on the nature of the repetition. These results suggest that successful encoding is predicted by a combination of increases and decreases in both the MTL activation and functional connectivity, and not merely by increases in activation and connectivity as suggested previously.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.