Evidence map›Paper›PMID 22254114›Full record

ReviewNutrients2011

Lactobacillus adhesion to mucus.

Maxwell L Van Tassell, Michael J Miller

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04907877 (Role of Nutritional Support With Probiotics in Adult Outpatients With Symptomatic COVID-19), which is not on this map. Cited by 133 papers.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed
18.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04907877 nacompletednot on this mapstarted 2021, after this paper: background citation

Role of Nutritional Support With Probiotics in Adult Outpatients With Symptomatic COVID-19: a Randomized Dietary Study

TypeinterventionalSponsorNordic Biotic Sp. z o.o.Ran2021 to 2023Enrolled70ConditionsCOVID-19 Respiratory InfectionArmsProbiotic, Placebo
3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 322 citations in OpenAlex.

  1. Review
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  16. Effect ofFoods (Basel, Switzerland) · 2025
    Article
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  18. Genomic Face-off: AnCurrent genomics · 2025
    Article
  19. Review
  20. Article

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maxwell L Van TassellDepartment of Food Science and Human Nutrition, University of Illinois, 905 S. Goodwin Ave., Urbana, IL 61801, USA. vantass2@illinois.edu
Michael J Miller
University of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucus provides protective functions in the gastrointestinal tract and plays an important role in the adhesion of microorganisms to host surfaces. Mucin glycoproteins polymerize, forming a framework to which certain microbial populations can adhere, including probiotic Lactobacillus species. Numerous mechanisms for adhesion to mucus have been discovered in lactobacilli, including partially characterized mucus binding proteins. These mechanisms vary in importance with the in vitro models studied, which could significantly affect the perceived probiotic potential of the organisms. Understanding the nature of mucus-microbe interactions could be the key to elucidating the mechanisms of probiotic adhesion within the host.

Indexed as

Bacterial AdhesionProbioticsBacterial ProteinsCarrier ProteinsHumansIntestinal MucosaLactobacillusMucinsMucusBacterial ProteinsCarrier ProteinsMucinsadhesionbindinglactobacillusMUC2MucBPmucinmucusprobiotics

Identifiers

PMID22254114
PMCPMC3257693
OpenAlexW2130590658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.