Evidence map›Paper›PMID 22101040›Full record

ArticleApplied and environmental microbiology2012

Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus.

Johannes Schneider, Ana Yepes, Juan C Garcia-Betancur, Isa Westedt, Benjamin Mielich, Daniel López

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The genome ofFrontiers in microbiology · 2023
    Article
  5. Review
  6. Review
  7. Review
  8. Novel Quorum Quenching YtnP Lactonase FromFrontiers in microbiology · 2022
    Article
  9. Marine drugs · 2021
    Article
  10. Attenuation ofAntibiotics (Basel, Switzerland) · 2021
    Article
  11. Exploration of the Quorum-Quenching Mechanism inFrontiers in microbiology · 2021
    Article
  12. Article
  13. Quorum Quenching Activity of the PGPRFrontiers in microbiology · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Draft Genome Sequences ofGenome announcements · 2017
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Johannes SchneiderInstitute for Molecular Infection Biology IMIB, Centre for Molecular Research in Infectious Disease ZINF, University of Würzburg, Würzburg, Germany.
Ana Yepes
Juan C Garcia-Betancur
Isa Westedt
Benjamin Mielich
Daniel López
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacillus subtilis induces expression of the gene ytnP in the presence of the antimicrobial streptomycin, produced by the Gram-positive bacterium Streptomyces griseus. ytnP encodes a lactonase-homologous protein that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus.

Indexed as

Gene Expression Regulation, BacterialGene Expression Regulation, EnzymologicAmino Acid SequenceBacillus subtilisCarboxylic Ester HydrolasesGene Expression ProfilingMolecular Sequence DataStreptomyces griseusStreptomycinCarboxylic Ester Hydrolasesdelta-lactonaseStreptomycin

Identifiers

PMID22101040
PMCPMC3255736
OpenAlexW2071715150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.