ArticleNature neuroscience2011
Evolutionary differences in food preference rely on Gr64e, a receptor for glycerol.
Article in Nature neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 101 citations in OpenAlex.
- Article
- Gustatory function of Aedes aegypti opsins and TRPA1 in avoiding a natural insect repellent.Current biology : CB · 2026Article
- Finding a path: local search behavior of Drosophila larvae.The Journal of experimental biology · 2025Article
- Molecular evolution of gustatory receptors in the Anopheles gambiae complex.BMC ecology and evolution · 2025Article
- Amino acids activate parallel chemosensory pathways in Drosophila.Chemical senses · 2025Article
- Characterization of the chemoreceptor repertoire of a highly specialized fly with comparisons to other Drosophila species.Genetics and molecular biology · 2024Article
- Article
- Increased sugar valuation contributes to the evolutionary shift in egg-laying behavior of the fruit pest Drosophila suzukii.PLoS biology · 2023Article
- Evolution of fatty acid taste in drosophilids.Cell reports · 2023Article
- Alkaline taste sensation through the alkaliphile chloride channel in Drosophila.Nature metabolism · 2023Article
- Adaptation ofeLife · 2022Article
- Ir56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila.Current biology : CB · 2022Article
- AThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Mechanisms of Carboxylic Acid Attraction inMolecules and cells · 2021Article
- Dietary Macronutrient Imbalances Lead to Compensatory Changes in Peripheral Taste via Independent Signaling Pathways.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Genome-Wide Identification of the Gustatory Receptor Gene Family of the Invasive Pest, Red Palm Weevil,Insects · 2021Article
- Article
- Review
- Persistence of a Yeast-Based (Insects · 2020Article
- Recent advances in the genetic basis of taste detection in Drosophila.Cellular and molecular life sciences : CMLS · 2020Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Very little is known about how stimuli that are typically not rich in sugars, such as beer, trigger attractive gustatory responses in Drosophila. We identified a member of the gustatory receptor family, Gr64e, as a receptor that is required for feeding preference for beer and other sources that have fermenting yeast. We found that Gr64e is required for neuronal and behavioral responses to glycerol, an abundant component of growing yeast and fermentation products. Ectopic expression of Gr64e in an olfactory neuron conferred responsiveness to glycerol. We also found that Drosophila species that are predicted to carry pseudogenes of Gr64e had reduced glycerol sensitivity. Our results provide insight into the molecular mechanisms of feeding acceptance of yeast products and raise the possibility that Gr64e contributes to specific evolutionary variations in appetitive selectivity across Drosophila species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.