ArticleThe Journal of clinical investigation2011
Dietary nitrate, nitric oxide, and restenosis.
Article in The Journal of clinical investigation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Does dietary nitrate boost the effects of caloric restriction on brain health? Potential physiological mechanisms and implications for future research.Nutrition & metabolism · 2023Review
- Content of nitric oxide and glycative compounds in cured meat products-Negative impact upon health.BioMedicine · 2018Article
- Impact of mitochondrial nitrite reductase on hemodynamics and myocardial contractility.Scientific reports · 2017Article
- Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health.Free radical biology & medicine · 2017Review
- Enhancing Stent Effectiveness with Nanofeatures.Methodist DeBakey cardiovascular journal · 2016Review
- Modulating DDAH/NOS Pathway to Discover Vasoprotective Insulin Sensitizers.Journal of diabetes research · 2016Review
- Proton pump inhibitors and vascular function: A prospective cross-over pilot study.Vascular medicine (London, England) · 2015Article
- Asymmetric dimethylarginine, race, and mortality in hemodialysis patients.Clinical journal of the American Society of Nephrology : CJASN · 2014Article
- Characterization of a fluorescent probe for imaging nitric oxide.Journal of vascular research · 2014Article
- FXR agonist INT-747 upregulates DDAH expression and enhances insulin sensitivity in high-salt fed Dahl rats.PloS one · 2013Article
- Reciprocal regulation of cellular nitric oxide formation by nitric oxide synthase and nitrite reductases.Medical science monitor : international medical journal of experimental and clinical research · 2011Review
- DDAH says NO to ADMA.Arteriosclerosis, thrombosis, and vascular biology · 2011Article
- Endothelium-Derived Nitric Oxide as an Antiatherogenic Mechanism: Implications for Therapy.Methodist DeBakey cardiovascular journalReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Endothelium-derived NO controls the contractility and growth state of the underlying vascular smooth muscle cells and regulates the interaction of the vessel wall with circulating blood elements. Acute injury of the vessel wall denudes the endothelial lining, removing homeostatic regulation and precipitating a wave of events leading to myointimal hyperplasia. In this issue of the JCI, Alef and colleagues provide evidence that in the injured vessel wall, the disruption of the NOS pathway is countered by induction of xanthine oxidoreductase, an enzyme capable of producing NO from nitrite. In addition, they link low dietary nitrite levels to increased severity of myointimal hyperplasia following vessel injury in mice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.