ReviewIndian journal of pediatrics2008
Strategies for minimizing corticosteroid toxicity: a review.
Review in Indian journal of pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Acute Neurological Complications of Brain Tumors and Immune Therapies, a Guideline for the Neuro-hospitalist.Current neurology and neuroscience reports · 2020Guideline
- Steroid myopathy and rehabilitation in patients with cancer.PM & R : the journal of injury, function, and rehabilitation · 2024Review
- Neurodevelopment in Term Infants with Normal Birthweight following Postnatal Systemic Steroid Exposure.Neuroepidemiology · 2024Article
- Modifiable contributing factors to COVID-19: A comprehensive review.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023Review
- Corticosteroids in ophthalmology: drug delivery innovations, pharmacology, clinical applications, and future perspectives.Drug delivery and translational research · 2021Review
- Polyphenols Extracted from Shanxi-Aged Vinegar Inhibit Inflammation in LPS-Induced RAW264.7 Macrophages and ICR Mice via the Suppression of MAPK/NF-κB Pathway Activation.Molecules (Basel, Switzerland) · 2021Article
- Novel function of adrenocorticotropic hormone in the stimulation of vascular endothelial growth factor release in healthy children and adolescents: a proof-of-concept study.Annals of pediatric endocrinology & metabolism · 2021Article
- Therapeutic and Prognostic Implications of Immune-Related Adverse Events in Advanced Non-Small-Cell Lung Cancer.Frontiers in oncology · 2021Article
- Evaluation of Urinary Tract Infection following Corticosteroid Therapy in Patients with Multiple Sclerosis Exacerbation.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021Article
- Clinical comparisons between previously diagnosed SLE and newly diagnosed SLE by kidney biopsy.Auto- immunity highlights · 2020Article
- A National Consensus Survey for Current Practice in Brain Tumor Management I: Antiepileptic Drug and Steroid Usage.Brain tumor research and treatment · 2020Article
- Dexamethasone Treatment at the Myoblast Stage Enhanced C2C12 Myocyte Differentiation.International journal of medical sciences · 2017Article
- Clinical analysis of chinese patients with rheumatoid arthritis treated with leflunomide and methotrexate combined with different dosages of glucocorticoid.Current therapeutic research, clinical and experimental · 2012Article
- Corticosteroid-use in primary and secondary brain tumour patients: a review.Journal of neuro-oncology · 2012Review
- SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glucocorticoids (GCs) are used commonly for the treatment of various pediatric inflammatory and autoimmune diseases. Although potent and generally effective, they are not without risks for producing serious adverse effects, especially when used in high doses for prolonged periods of time. For proper use of systemic glucocortcoids, a basic knowledge of the pharmacology, clinical usage guidelines, and adverse reactions of these agents is imperative. This review article emphasis on the commonly observed side-effects encountered with GC use in children and their underlying basic pathophysiological mechanisms. The appropriate anticipation of these side-effects with timely implementation of the suggested evidencebased guidelines has the potential significantly to prevent, minimize and treat common and disabling complications of glucocortcoid therapy.
Indexed as
Identifiers
19023531What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.