ArticlePlant biotechnology journal2008
Low-acrylamide French fries and potato chips.
Article in Plant biotechnology journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 150 citations in OpenAlex.
- Development of a qualitative detection method for the pSIM1278 construct in genetically modified potato using real-time PCR.GM crops & food · 2026Article
- Genetic architecture of tuber-bound free amino acids in potato and effect of growing environment on the amino acid content.Scientific reports · 2023Article
- Functional Food Based on Potato.Foods (Basel, Switzerland) · 2023Review
- Multiplex CRISPR-Cas9 Gene-Editing Can Deliver Potato Cultivars with Reduced Browning and Acrylamide.Plants (Basel, Switzerland) · 2023Article
- Cisgenics and intragenics: boon or bane for crop improvement.Frontiers in plant science · 2023Review
- Effect of Betaine on Blood Parameters Related to the Iron Status in Acrylamide-Treated Rats.Archives of Razi Institute · 2022Article
- Genetic Improvement of Wheat for Drought Tolerance: Progress, Challenges and Opportunities.Plants (Basel, Switzerland) · 2022Review
- Genome Editing Technology for Genetic Amelioration of Fruits and Vegetables for Alleviating Post-Harvest Loss.Bioengineering (Basel, Switzerland) · 2022Review
- Nicotiana benthamiana asparagine synthetase associates with IP-L and confers resistance against tobacco mosaic virus via the asparagine-induced salicylic acid signalling pathway.Molecular plant pathology · 2022Article
- The Intragenesis and Synthetic Biology Approach towards Accelerating Genetic Gains on Strawberry: Development of New Tools to Improve Fruit Quality and Resistance to Pathogens.Plants (Basel, Switzerland) · 2021Article
- Potato improvement through genetic engineering.GM crops & food · 2021Review
- Can gene editing reduce postharvest waste and loss of fruit, vegetables, and ornamentals?Horticulture research · 2021Review
- Roasted Rye as a Coffee Substitute: Methods for Reducing Acrylamide.Foods (Basel, Switzerland) · 2020Article
- Potato Tuber Chemical Properties in Storage as Affected by Cultivar and Nitrogen Rate: Implications for Acrylamide Formation.Foods (Basel, Switzerland) · 2020Article
- Acrylamide in food: Progress in and prospects for genetic and agronomic solutions.The Annals of applied biology · 2019Article
- Genetic strategies for improving crop yields.Nature · 2019Review
- Influence of Potato Crisps Processing Parameters on Acrylamide Formation and Bioaccesibility.Molecules (Basel, Switzerland) · 2019Article
- Article
- RNA Silencing in Plants: Mechanisms, Technologies and Applications in Horticultural Crops.Current genomics · 2016Article
- Genetically modified (GM) crops: milestones and new advances in crop improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2016Review
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryAcrylamide is produced in starchy foods that are baked, roasted or fried at high temperatures. Concerns about the potential health issues associated with the dietary intake of this reactive compound led us to reduce the accumulation of asparagine, one of its main precursors, in the tubers of potato (Solanum tuberosum). This metabolic change was accomplished by silencing two asparagine synthetase genes through 'all-native DNA' transformation. Glasshouse-grown tubers of the transformed intragenic plants contained up to 20-fold reduced levels of free asparagine. This metabolic change coincided with a small increase in the formation of glutamine and did not affect tuber shape or yield. Heat-processed products derived from the low-asparagine tubers were also indistinguishable from their untransformed counterparts in terms of sensory characteristics. However, both French fries and potato chips accumulated as little as 5% of the acrylamide present in wild-type controls. Given the important role of processed potato products in the modern Western diet, a replacement of current varieties with intragenic potatoes could reduce the average daily intake of acrylamide by almost one-third.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.