ArticleUgeskrift for laeger2006
[High-dose atorvastatin or normal-dose simvastatin in treatment of patients with coronary heart disease (IDEAL trial)--secondary publication].
Article in Ugeskrift for laeger, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Abstract
In the IDEAL trial, almost 9,000 patients with coronary heart disease were treated, after randomisation, with atorvastatin, 80 mg daily, or simvastatin, 20 or 40 mg daily, for 4.8 years. The LDL cholesterol level was 0.6 mmol/l lower in the atorvastatin group, a smaller difference than expected, and the 11% reduction in the primary end point (myocardial infarction, cardiac arrest, coronary death) in this group was not statistically significant (p = 0.07). In contrast, several secondary end points, one of which was the primary end point plus stroke, occurred statistically significantly less often in the atorvastatin group.
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16729930What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.