Evidence map›Paper›PMID 12479771›Full record

ArticleJAMA2002

The ALLHAT lipid lowering trial--less is less.

Richard C Pasternak

Registry-linked trialAbstract readCommentEditorial
PubMed Publisher
In one paragraph

Article in JAMA, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT00000542. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00000542 phase3completed

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

Ran1993Registered outcomes0Posted comparisons0ConditionsCardiovascular Diseases, Coronary Disease, Diabetes Mellitus, Heart DiseasesArmsamlodipine, chlorthalidone, diet, fat-restricted, doxazosin, Inhibitors, ACE
Open the trial in the graph
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. A comprehensive review on metabolic syndrome.Cardiology research and practice · 2014
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Managing cardiovascular risk in minority patients.Journal of the National Medical Association · 2005
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Richard C Pasternak

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anticholesteremic AgentsCardiovascular DiseasesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaHypertensionPravastatinAnticholesteremic AgentsHydroxymethylglutaryl-CoA Reductase InhibitorsPravastatin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.