Evidence map›Paper›PMID 11684524›Full record

SynthesisThe American journal of clinical nutrition2001

Long-term weight-loss maintenance: a meta-analysis of US studies.

J W Anderson, E C Konz, R C Frederich, C L Wood

9 registry-linked trialsAbstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in The American journal of clinical nutrition, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 477 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
477citing papers in PubMed, 14 pooled it
23.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04122716 phase4unknown statusstarted 2016, after this paper: background citation

Synergy Effect of the Appetite Hormone GLP-1 (LiragluTide) and Exercise on Maintenance of Weight Loss and Health After a Low Calorie Diet - the S-LiTE Randomized Trial

Ran2016Enrolled215Registered outcomes28Posted comparisons0ConditionsObesityArmsExercise, liraglutide
PMID 23186644PMID 26132939PMID 26284720PMID 28049736PMID 30052921PMID 27295427PMID 27633186PMID 25287751PMID 23812094PMID 25197563PMID 11234459PMID 11812755other papers from this trial
Open the trial in the graph
NCT02635659 nacompletednot on this mapstarted 2015, after this paper: background citation

The Effect of an Encapsulated Nutrient Mixture on Ileal Brake Activation: A Double-blind Randomized Study to Investigate the Effects on Body Weight, Food Intake and Satiety.

TypeinterventionalSponsorMaastricht University Medical CenterRan2015 to 2016Enrolled62ConditionsBody Weight DecreasedArmsEncapsulated nutrients, Placebo
NCT03463213 naunknown statusnot on this mapstarted 2018, after this paper: background citation

She's Healthy and Empowered (SHE Tribe): A Social Networked-based Peer-facilitated Intervention to Improve Health Behavior Among Women in Underserved Communities

TypeinterventionalSponsorUniversity of North Texas Health Science CenterRan2018 to 2020Enrolled240ConditionsHealth PromotionArmsSHE Tribe
NCT04807959 completednot on this mapstarted 2016, after this paper: background citation

A Retrospective Study to Evaluate the Effectiveness of a Comprehensive Visceral Adiposity-Focused Anti-Obesity Program

TypeobservationalSponsor20LighterRan2016 to 2018Enrolled2,200ConditionsObesity, Obesity, Morbid, Obesity, Visceral, Central ObesityArms20Lighter anti-obesity program
NCT05219240 unknown statusnot on this mapstarted 2020, after this paper: background citation

Evaluation of Body Composition Improvement With Visceral Adiposity-Focused Anti-Obesity Telehealth Program

TypeobservationalSponsor20LighterRan2020 to 2024Enrolled2,000ConditionsObesity, Cardiovascular Diseases, Metabolic Syndrome, Metabolic DiseaseArms20Lighter Program
NCT05874726 active not recruitingnot on this mapstarted 2023, after this paper: background citation

Biological Sample Repository for Gastrointestinal Disorders

Typeobservational_patient_registrySponsorPichamol Jirapinyo, MD, MPHRan2023 to 2029Enrolled500ConditionsObesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal DisorderArmsBlood Collection, Urine Collection, Tissue Sample Collection
NCT05927337 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Cognitive-Behavioral Therapy for Managing Obesity in People With Chronic Kidney Disease

TypeinterventionalSponsorUniversity Medical Centre LjubljanaRan2023 to 2025Enrolled60ConditionsChronic Kidney Diseases, Obesity, OverweightArmsCognitive Behavioral Therapy (CBT) for managing Obesity
NCT06934681 narecruitingnot on this mapstarted 2025, after this paper: background citation

Impact of a Structured Physical Exercise Program on Body Composition in Morbid Obesity: A Randomized Controlled Trial

TypeinterventionalSponsorInstituto de Investigacion Sanitaria La FeRan2025 to 2029Enrolled72ConditionsMorbid Obesity, Bariatric Surgery, TelerehabilitationArmsUsual Care Group, Controlled exercise with telerehabilitation
NCT07739095 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Weight Loss and Hunger: Did we Get it Wrong All This Time?

TypeinterventionalSponsorUniversity of OttawaRan2026 to 2028Enrolled40ConditionsObesity & OverweightArmsExercise, Dietary Intervention
3 · Its place in the literature

Who cites it

477 citing papers in PubMed, 14 syntheses or guidelines pooled it, 1,339 citations in OpenAlex.

  1. Effect of Citrus bergamia Supplementation on Body Composition in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  8. Emotional Eating Interventions for Adults Living With Overweight and Obesity: A Systematic Review and Meta-Analysis of Behaviour Change Techniques.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Pooled it
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  12. Effects of total diet replacement programs on mental well-being: A systematic review with meta-analyses.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
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  14. Does exercise affect bone mineral density and content when added to a calorie-restricted diet? A systematic review and meta-analysis of controlled clinical trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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  19. Exercise and QUality Diet after Leukemia: A Randomized Weight Loss Trial among Adult Survivors of Childhood Leukemia in the Childhood Cancer Survivor Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
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417 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

J W AndersonVA Medical Center, Graduate Center for Nutritional Sciences, University of Kentucky Health Management Resources Weight Management Program, Lexington, KY, USA. jwandersmd@aol.com
E C Konz
R C Frederich
C L Wood
University of Kentucky · USThe Graduate Center, CUNY · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent perception is that participants of a structured weight-loss program regain all of their weight loss within 5 y.

objectiveThe objective was to examine the long-term weight-loss maintenance of individuals completing a structured weight-loss program.

designStudies were required to 1) have been conducted in the United States, 2) have included participants in a structured weight-loss program, 3) have provided follow-up data with variance estimates for > or =2 y. Primary outcome variables were weight-loss maintenance in kilograms, weight-loss maintenance as a percentage of initial weight loss, and weight loss as a percentage of initial body weight (reduced weight).

resultsTwenty-nine studies met the inclusion criteria. Successful very-low-energy diets (VLEDs) were associated with significantly greater weight-loss maintenance than were successful hypoenergetic balanced diets (HBDs) at all years of follow-up. The percentage of individuals at 4 or 5 y of follow-up for VLEDs and HBDs were 55.4% and 79.7%, respectively. The results for VLEDs and HBDs, respectively, were as follows: weight-loss maintenance, 7.1 kg (95% CI: 6.1, 8.1 kg) and 2.0 (1.5, 2.5) kg; percentage weight-loss maintenance, 29% (25%, 33%) and 17% (13%, 22%); and reduced weight, 6.6% (5.7%, 7.5%) and 2.1% (1.6%, 2.7%). Weight-loss maintenance did not differ significantly between women and men. Six studies reported that groups who exercised more had significantly greater weight-loss maintenance than did those who exercised less.

conclusionsFive years after completing structured weight-loss programs, the average individual maintained a weight loss of >3 kg and a reduced weight of >3% of initial body weight. After VLEDs or weight loss of > or =20 kg, individuals maintained significantly more weight loss than after HBDs or weight losses of <10 kg.

Indexed as

Diet, ReducingExerciseWeight LossAdultBody WeightEnergy IntakeFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMEDLINEMiddle AgedObesityTreatment OutcomeUnited States

Identifiers

PMID11684524
OpenAlexW2097309757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.