Diuretics vs alpha-blockers for treatment of hypertension: lessons from ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Who cites it

11 citing papers in PubMed, 38 citations in OpenAlex.

1. The I1-imidazoline agonist moxonidine decreases sympathetic tone under physical and mental stress.British journal of clinical pharmacology · 2004
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2. Novel therapies for diabetic kidney disease.Kidney international supplements · 2018
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3. MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.The Journal of cell biology · 2012
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4. Newer is not always better: all antihypertensive medications do not equally reduce cardiovascular risk.Journal of general internal medicine · 2012
   Article
5. Doxazosin gastrointestinal therapeutic system: a review of its use in benign prostatic hyperplasia.Drugs · 2005
   Review
6. Diastolic Dysfunction.Current treatment options in cardiovascular medicine · 2004
   Article
7. Candesartan cilexetil plus hydrochlorothiazide combination: a review of its use in hypertension.Drugs · 2002
   Review
8. Diastolic heart failure in the elderly.Heart failure reviews · 2002
   Review
9. Recent clinical trial highlights in hypertension.Current hypertension reports · 2001
   Review
10. Telmisartan: a review of its use in hypertension.Drugs · 2001
    Review
11. Concentration-controlled or effect-controlled trials: useful alternatives to conventional dose-controlled trials?Clinical pharmacokinetics · 2001
    Review

Corrections and comments

• Comment on
  Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group.2000

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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