Evidence map›Paper›PMID 9990047›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1999

Organization of an echinoderm Hox gene cluster.

P Martinez, J P Rast, C Arenas-Mena, E H Davidson

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
26.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 84 citations in OpenAlex.

  1. Expression of HOX Cluster Genes in Early Larval Development of Sea Urchin Strongylocentrotus intermedius (Echinodermata, Echinoidea).Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2025
    Article
  2. Analysis of theCell genomics · 2023
    Article
  3. A roadmap for intestinal regeneration.The International journal of developmental biology · 2021
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Evolution of invertebrate deuterostomes and Hox/ParaHox genes.Genomics, proteomics & bioinformatics · 2011
    Review
  12. Review
  13. Article
  14. Hox genes are not always Colinear.International journal of biological sciences · 2006
    Review
  15. Article
  16. Article
  17. Article
  18. Molecular evolution of the HoxA cluster in the three major gnathostome lineages.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  19. HOX genes in the sepiolid squid Euprymna scolopes: implications for the evolution of complex body plans.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
  20. Dynamic expression of multiple scavenger receptor cysteine-rich genes in coelomocytes of the purple sea urchin.Proceedings of the National Academy of Sciences of the United States of America · 2000
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

P MartinezDivision of Biology, California Institute of Technology, Pasadena, CA 91125, USA.
J P Rast
C Arenas-Mena
E H Davidson
California Institute of Technology · US

Funding

ADVANCED TRAINING IN MOLECULAR BIOLOGY OF DEVELOPMENTT32HD007257 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI DAVIDSON, ERIC H · 1985 to 2002
$317k
NICHD NIH HHS HD-07257NICHD NIH HHS T32 HD007257
6 · The paper itself

Abstract

The Strongylocentrotus purpuratus genome contains a single ten-gene Hox complex >0.5 megabase in length. This complex was isolated on overlapping bacterial artificial chromosome and P1 artificial chromosome genomic recombinants by using probes for individual genes and by genomic walking. Echinoderm Hox genes of Paralog Groups (PG) 1 and 2 are reported. The cluster includes genes representing all paralog groups of vertebrate Hox clusters, except that there is a single gene of the PG4-5 types and only three genes of the PG9-12 types. The echinoderm Hox gene cluster is essentially similar to those of the bilaterally organized chordates, despite the radically altered pentameral body plans of these animals.

Indexed as

Evolution, MolecularGenes, HelminthGenes, HomeoboxMultigene FamilyPhylogenyAmino Acid SequenceAnimalsChromosomes, BacterialConsensus SequenceDrosophilaGenomeMolecular Sequence DataSequence AlignmentSequence Homology, Amino AcidStrongyloideaVertebrates

Identifiers

PMID9990047
PMCPMC15486
OpenAlexW2139728683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.