ArticleJournal of bacteriology1999
The virulence plasmid of Salmonella typhimurium is self-transmissible.
Article in Journal of bacteriology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 118 citations in OpenAlex.
- Challenges and considerations for whole-genome-based antimicrobial resistance plasmid investigations.Antimicrobial agents and chemotherapy · 2025Review
- Resistance, virulence and genetic diversity of Salmonella Typhimurium in South Africa (1999-2021).The Onderstepoort journal of veterinary research · 2025Article
- Detection and Correlation of Virulence Determinants of Ampicillin Resistant Isolates ofIndian journal of microbiology · 2025Article
- Potential links between human bloodstream infection by Salmonella enterica serovar Typhimurium and international transmission to Colombia.PLoS neglected tropical diseases · 2025Article
- Infection biology ofEcoSal Plus · 2024Review
- Article
- Unveiling genome plasticity and a novel phage inMicrobial genomics · 2024Article
- Plasmids pick a bacterial partner before committing to conjugation.Nucleic acids research · 2023Review
- Conditions Necessary for the Transfer of Antimicrobial Resistance in Poultry Litter.Antibiotics (Basel, Switzerland) · 2023Article
- A global survey ofMicrobial genomics · 2023Article
- The Interaction of the F-Like Plasmid-Encoded TraN Isoforms with Their Cognate Outer Membrane Receptors.Journal of bacteriology · 2023Article
- Article
- Whole-genome sequencing of multidrug resistanceFrontiers in public health · 2023Article
- Identification and genetic characterization of two conjugative plasmids that confer azithromycin resistance inEmerging microbes & infections · 2022Article
- Bacterial plasmid-associated and chromosomal proteins have fundamentally different properties in protein interaction networks.Scientific reports · 2022Article
- Understanding the Mechanism of Antimicrobial Resistance and Pathogenesis ofMicroorganisms · 2022Review
- Contrasting long-term dynamics of antimicrobial resistance and virulence plasmids inMicrobial genomics · 2022Article
- Mating pair stabilization mediates bacterial conjugation species specificity.Nature microbiology · 2022Article
- Genome analysis and virulence gene expression profile of a multi drug resistant Salmonella enterica serovar Typhimurium ms202.Gut pathogens · 2022Article
- Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements.Nature communications · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Most isolates of Salmonella enterica serovar Typhimurium contain a 90-kb virulence plasmid. This plasmid is reported to be mobilizable but nonconjugative. However, we have determined that the virulence plasmid of strains LT2, 14028, and SR-11 is indeed self-transmissible. The plasmid of strain SL1344 is not. Optimal conjugation frequency requires filter matings on M9 minimal glucose plates with a recipient strain lacking the virulence plasmid. These conditions result in a frequency of 2.9 x 10(-4) transconjugants/donor. Matings on Luria-Bertani plates, liquid matings, or matings with a recipient strain carrying the virulence plasmid reduce the efficiency by up to 400-fold. Homologs of the F plasmid conjugation genes are physically located on the virulence plasmid and are required for the conjugative phenotype.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.