ArticleDigestive diseases and sciences1999
One stomach--one strain: does Helicobacter pylori strain variation influence disease outcome?
Article in Digestive diseases and sciences, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 47 citations in OpenAlex.
- Identification, Genome Sequencing, and Characterizations ofMicroorganisms · 2023Article
- Heterogeneity ofInfection and drug resistance · 2021Article
- PCR Based Detection of Phase Variable Genes in Pakistani Based Clinical Helicobacter pylori Strains.Jundishapur journal of microbiology · 2016Article
- Analysis of clinical isolates of Helicobacter pylori in Pakistan reveals high degrees of pathogenicity and high frequencies of antibiotic resistance.Helicobacter · 2014Article
- Association between cagA and vacA genotypes and pathogenesis in a Helicobacter pylori infected population from South-eastern Sweden.BMC microbiology · 2012Article
- Lipopolysaccharide diversity evolving in Helicobacter pylori communities through genetic modifications in fucosyltransferases.PloS one · 2008Article
- An enzymatic ruler modulates Lewis antigen glycosylation of Helicobacter pylori LPS during persistent infection.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Slow genetic divergence of Helicobacter pylori strains during long-term colonization.Infection and immunity · 2005Article
- Genotypic and phenotypic stability of Helicobacter pylori markers in a nine-year follow-up study of patients with noneradicated infection.Digestive diseases and sciences · 2005Article
- High prevalence of multiple strain colonization of Helicobacter pylori in Korean patients: DNA diversity among clinical isolates from the gastric corpus, antrum and duodenum.The Korean journal of internal medicine · 2004Article
- Concordance of Helicobacter pylori strains within families.Journal of clinical microbiology · 2003Article
- Correlation between cag pathogenicity island composition and Helicobacter pylori-associated gastroduodenal disease.Infection and immunity · 2003Article
- Infection with cagA-positive and cagA-negative types of Helicobacter pylori among children and adolescents with gastrointestinal symptoms in Latvia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2003Article
- Comparison of genetic divergence and fitness between two subclones of Helicobacter pylori.Infection and immunity · 2001Article
- Consensus and variable region PCR analysis of Helicobacter pylori 3' region of cagA gene in isolates from individuals with or without peptic ulcer.Journal of clinical microbiology · 2001Article
- Clustering of clinical strains of Helicobacter pylori analyzed by two-dimensional gel electrophoresis.Clinical and diagnostic laboratory immunology · 2000Article
- Rapid PCR detection of Helicobacter pylori-associated virulence and resistance genes directly from gastric biopsy material.Journal of clinical microbiology · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to determine inter- and intrapatient variation of Helicobacter pylori strains based on genomic fingerprinting and cagA (cytotoxin-associated gene A) status. Ten bacterial colonies from each of 10 patients with gastric cancer (GC), 10 with duodenal ulcer (DU), and 10 with gastritis (GI) were used. The presence of the putative adhesin gene, the cagA gene, and the strain specific banding pattern obtained by arbitrary primed (AP-) PCR was analyzed. Genomic fingerprinting showed extensive interpatient variation, but the banding patterns obtained from colonies from the same patient were always identical (intrapatient variation). In five patients, the cagA status varied between the colonies despite identical banding patterns. Among patients in a developed country such as Sweden, the proportion with multiple-strain infection of H. pylori is low, but subclones with differing cagA status exist within the strain.
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