Evidence map›Paper›PMID 9929759›Full record

ArticleClinical cardiology1999

Microphysiology of the pericardium in relation to intrapericardial therapeutics and diagnostics.

D H Spodick

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cardiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Intrapericardial therapy and diagnosis.Current cardiology reports · 2002
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

D H SpodickUniversity of Massachusetts Medical School, Cardiology Division, St. Vincent Hospital, Worcester, USA.
St Vincent Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrapericardial delivery of therapeutic agents for pericardial diseases has long been available in the presence of excess pericardial fluid. Most patients with myocardial and coronary disease have no such excess so that their direct treatment requires pericardial access, for which a new instrument has succeeded in animals with induced infarctions, coronary lesions and arrhythmias. Nitric oxide (NO) donors, calcium-avid drugs, antibodies, angiogenic agents (pharmacologic coronary bypass), and hypothermic solutions have been instilled intrapericardially, and even iontophoresis has been used; gene therapy is also promising. Intrinsic pericardiogenic substances may potentially be stimulated for comparable purposes.

Indexed as

Angiogenesis Inducing AgentsAnimalsAntibodiesArrhythmias, CardiacCalciumCardiomyopathiesCoronary DiseaseDisease Models, AnimalGenetic TherapyHypothermia, InducedInjectionsIontophoresisMyocardial InfarctionNitric Oxide DonorsPericardiumAngiogenesis Inducing AgentsAntibodiesCalciumNitric Oxide Donors

Identifiers

PMID9929759
PMCPMC6656076
OpenAlexW2125785793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.