ArticleThe Plant cell1999
Phenotype of the tomato high pigment-2 mutant is caused by a mutation in the tomato homolog of DEETIOLATED1.
Article in The Plant cell, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.
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Who cites it
103 citing papers in PubMed, 283 citations in OpenAlex.
- Loss of DET1 in High Pigment 2 Tomato Prevents High Temperature Repression of Anthocyanin Biosynthesis in Fruit Through HY5 Stabilization.Plant, cell & environment · 2026Article
- Cyanobacterial biostimulants boost tomato (Solanum lycopersicum L.) Growth and drought tolerance for climate-resilient cropping systems.World journal of microbiology & biotechnology · 2026Article
- Tissue-specific profiles of phenolic metabolites in rice deprived ofFrontiers in plant science · 2026Article
- Molecular breeding of tomato: Advances and challenges.Journal of integrative plant biology · 2025Review
- The resistance ofPhotosynthetica · 2025Article
- Enhancing drought tolerance inFrontiers in plant science · 2025Article
- Genetic and Biotechnological Approaches to Improve Fruit Bioactive Content: A Focus on Eggplant and Tomato Anthocyanins.International journal of molecular sciences · 2024Review
- Feruloyl Glyceride Mitigates Tomato Postharvest Rot by InhibitingFoods (Basel, Switzerland) · 2024Article
- The potential of metabolomics in assessing global compositional changes resulting from the application of CRISPR/Cas9 technologies.Transgenic research · 2023Article
- Marker assisted early generation identification of root knot disease resistant orange tomato segregants with multiple desirable alleles.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Genetic Mechanisms for Hybrid Breeding in Vegetable Crops.Plants (Basel, Switzerland) · 2023Review
- Phytol recycling: essential, yet not limiting for tomato fruit tocopherol accumulation under normal growing conditions.Plant molecular biology · 2023Article
- Article
- Transcriptomic Analysis Suggests a Coordinated Regulation of Carotenoid Metabolism in Ripening Chili Pepper (Antioxidants (Basel, Switzerland) · 2022Article
- Elevated carbon assimilation and metabolic reprogramming in tomato high pigment mutants support the increased production of pigments.Plant cell reports · 2022Article
- TeaHorticulture research · 2022Article
- Phenotypic Characterization of High Carotenoid Tomato Mutants Generated by the Target-AID Base-Editing Technology.Frontiers in plant science · 2022Article
- Mutations inFrontiers in plant science · 2022Article
- SlZHD17 is involved in the control of chlorophyll and carotenoid metabolism in tomato fruit.Horticulture research · 2021Article
- GLABRA2-based selection efficiently enriches Cas9-generated nonchimeric mutants in the T1 generation.Plant physiology · 2021Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tomato high pigment (hp) mutants are characterized by their exaggerated photoresponsiveness. Light-grown hp mutants display elevated levels of anthocyanins, are shorter and darker than wild-type plants, and have dark green immature fruits due to the overproduction of chlorophyll pigments. It has been proposed that HP genes encode negative regulators of phytochrome signal transduction. We have cloned the HP-2 gene and found that it encodes the tomato homolog of the nuclear protein DEETIOLATED1 (DET1) from Arabidopsis. Mutations in DET1 are known to result in constitutive deetiolation in darkness. In contrast to det1 mutants, tomato hp-2 mutants do not display any visible phenotypes in the dark but only very weak phenotypes, such as partial chloroplast development. Furthermore, whereas det1 mutations are epistatic to mutations in phytochrome genes, analysis of similar double mutants in tomato showed that manifestation of the phenotype of the hp-2 mutant is strictly dependent upon the presence of active phytochrome. Because only one DET1 gene is likely to be present in each of the two species, our data suggest that the phytochrome signaling pathways in which the corresponding proteins function are regulated differently in Arabidopsis and tomato.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.