ArticleGenetics1999
Aspergillus nidulans swo mutants show defects in polarity establishment, polarity maintenance and hyphal morphogenesis.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 104 citations in OpenAlex.
- Azole resistance mechanisms and population structure of the human pathogenApplied and environmental microbiology · 2024Article
- Regulators of the Asexual Life Cycle ofCells · 2023Review
- Evidence for the agricultural origin of resistance to multiple antimicrobials in Aspergillus fumigatus, a fungal pathogen of humans.G3 (Bethesda, Md.) · 2022Article
- Sporulation environment drives phenotypic variation in the pathogen Aspergillus fumigatus.G3 (Bethesda, Md.) · 2021Article
- Stress-Activated Protein Kinase Signalling Regulates Mycoparasitic Hyphal-Hyphal Interactions inJournal of fungi (Basel, Switzerland) · 2021Article
- Characterization ofFrontiers in microbiology · 2019Article
- Altered secretion patterns and cell wall organization caused by loss of PodB function in the filamentous fungus Aspergillus nidulans.Scientific reports · 2018Article
- Fsr1, a striatin homologue, forms an endomembrane-associated complex that regulates virulence in the maize pathogen Fusarium verticillioides.Molecular plant pathology · 2018Article
- Cell Biology of Hyphal Growth.Microbiology spectrum · 2017Review
- Fungal morphogenesis.Cold Spring Harbor perspectives in medicine · 2014Review
- Characterization of the mutagenic spectrum of 4-nitroquinoline 1-oxide (4-NQO) in Aspergillus nidulans by whole genome sequencing.G3 (Bethesda, Md.) · 2014Article
- Laccases involved in 1,8-dihydroxynaphthalene melanin biosynthesis in Aspergillus fumigatus are regulated by developmental factors and copper homeostasis.Eukaryotic cell · 2013Article
- Structural features of sugars that trigger or support conidial germination in the filamentous fungus Aspergillus niger.Applied and environmental microbiology · 2013Article
- Quantifying the importance of galactofuranose in Aspergillus nidulans hyphal wall surface organization by atomic force microscopy.Eukaryotic cell · 2011Article
- Septins AspA and AspC are important for normal development and limit the emergence of new growth foci in the multicellular fungus Aspergillus nidulans.Eukaryotic cell · 2010Article
- Aspergillus nidulans protein O-mannosyltransferases play roles in cell wall integrity and developmental patterning.Eukaryotic cell · 2009Article
- The effect of temperature on Natural Antisense Transcript (NAT) expression in Aspergillus flavus.Current genetics · 2008Article
- A p21-activated kinase is required for conidial germination in Penicillium marneffei.PLoS pathogens · 2007Article
- Aspergillus nidulans conidiation genes dewA, fluG, and stuA are differentially regulated in early vegetative growth.Eukaryotic cell · 2007Article
- The SH3/PH domain protein AgBoi1/2 collaborates with the Rho-type GTPase AgRho3 to prevent nonpolar growth at hyphal tips of Ashbya gossypii.Eukaryotic cell · 2006Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When the spores of filamentous fungi break dormancy, they grow isotropically, adding cell wall material uniformly in every direction. Later they switch to polarized growth, with new material added to the tip of an emerging germ tube. To identify genes involved in the synthesis and localization of cell wall material in filamentous fungi, we screened a collection of temperature-sensitive Aspergillus nidulans mutants for swollen cells. We have isolated mutants representing eight genes involved in polarity establishment, polarity maintenance, and hyphal morphogenesis. On the basis of the results of temperature-shift experiments, swo C, D, and F are required to establish polarity, while swoA is required to maintain polarity. swo B, E, G, and H are involved in later hyphal morphogenesis. Our results suggest that polarity establishment and polarity maintenance are genetically separate events and that a persistent signal is required for apical extension in A. nidulans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.