ArticleAntimicrobial agents and chemotherapy1999
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-resistant and -susceptible Staphylococcus aureus strains.
Article in Antimicrobial agents and chemotherapy, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05027893 (Efficacy of the Application of Moxifloxacin and Cefixime in Reduction of Inflammatory Sequelae and Complications After Mandibular Third Molar Surgery), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of the Application of Moxifloxacin and Cefixime in Reduction of Inflammatory Sequelae and Complications After Mandibular Third Molar Surgery
Who cites it
19 citing papers in PubMed.
- Monotherapy with intravenous followed by oral high-dose ciprofloxacin versus combination therapy with ceftazidime plus amikacin as initial empiric therapy for granulocytopenic patients with fever.Antimicrobial agents and chemotherapy · 2000Trial
- Comparing the Synergistic and Antagonistic Interactions of Ciprofloxacin and Levofloxacin Combined with Rifampin against Drug-ResistantAntibiotics (Basel, Switzerland) · 2023Article
- Efficacy of antibiotic treatment of implant-associatedDrug design, development and therapy · 2017Article
- Bacterial Etiology and Antibiotic Resistance Profile of Community-Acquired Urinary Tract Infections in a Cameroonian City.International journal of microbiology · 2016Article
- Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus.PloS one · 2014Article
- In vitro activity and rodent efficacy of clinafloxacin for bovine and swine respiratory disease.Frontiers in microbiology · 2013Article
- Antistaphylococcal effect related to the area under the curve/MIC ratio in an in vitro dynamic model: predicted breakpoints versus clinically achievable values for seven fluoroquinolones.Antimicrobial agents and chemotherapy · 2005Article
- In vitro activity of the new quinolone WCK 771 against staphylococci.Antimicrobial agents and chemotherapy · 2004Article
- Moxifloxacin efficacy and vitreous penetration in a rabbit model of Staphylococcus aureus endophthalmitis and effect on gene expression of leucotoxins and virulence regulator factors.Antimicrobial agents and chemotherapy · 2003Article
- Determining Linezolid's baseline in vitro activity in Canada using gram-positive clinical isolates collected prior to its national release.Antimicrobial agents and chemotherapy · 2002Article
- Review
- Efficacies of moxifloxacin, ciprofloxacin, and vancomycin against experimental endocarditis due to methicillin-resistant Staphylococcus aureus expressing various degrees of ciprofloxacin resistance.Antimicrobial agents and chemotherapy · 2001Article
- Efficacy of linezolid in treatment of experimental endocarditis caused by methicillin-resistant Staphylococcus aureus.Antimicrobial agents and chemotherapy · 2001Article
- In vitro activities of six quinolones and mechanisms of resistance in Staphylococcus aureus and coagulase-negative staphylococci.Antimicrobial agents and chemotherapy · 2001Article
- Review
- Bactericidal activity of quinupristin-dalfopristin against Staphylococcus aureus: clindamycin susceptibility as a surrogate indicator.Antimicrobial agents and chemotherapy · 2000Article
- Linezolid.Drugs · 2000Review
- Review
- Quinupristin/dalfopristin: a review of its use in the management of serious gram-positive infections.Drugs · 1999Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The activities of eight fluoroquinolones and linezolid, quinupristin-dalfopristin (Synercid), gentamicin, and vancomycin were tested against 96 ciprofloxacin-susceptible and 205 ciprofloxacin-resistant Staphylococcus aureus strains. Overall, clinafloxacin, followed by moxifloxacin and trovafloxacin, was the most active quinolone tested. For all isolates, linezolid and quinupristin-dalfopristin showed activities that were at least comparable to vancomycin, with no cross-resistance to any other test compound.
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