ArticleAnnals of the rheumatic diseases1998
Influence of non-inherited maternal HLA-DR antigens on susceptibility to rheumatoid arthritis.
Article in Annals of the rheumatic diseases, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 45 citations in OpenAlex.
- Review
- Human Leukocyte Antigen-Disease Associations in Rheumatoid Arthritis.Rheumatic diseases clinics of North America · 2017Review
- The Quantitative-MFG Test: A Linear Mixed Effect Model to Detect Maternal-Offspring Gene Interactions.Annals of human genetics · 2016Article
- Review
- Article
- Parity and HLA alleles in risk of rheumatoid arthritis.Chimerism · 2011Article
- Modeling maternal-offspring gene-gene interactions: the extended-MFG test.Genetic epidemiology · 2010Article
- Evidence for maternal-fetal genotype incompatibility as a risk factor for schizophrenia.Journal of biomedicine & biotechnology · 2010Review
- Influence of HLA DRB1 alleles in the susceptibility of rheumatoid arthritis and the regulation of antibodies against citrullinated proteins and rheumatoid factor.Arthritis research & therapy · 2010Article
- Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes.Diabetes, obesity & metabolism · 2009Article
- Why are women predisposed to autoimmune rheumatic diseases?Arthritis research & therapy · 2009Review
- Non-inherited maternal human leukocyte antigen alleles in susceptibility to familial rheumatoid arthritis.Annals of the rheumatic diseases · 2009Article
- Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Using the maternal-fetal genotype incompatibility test to assess non-inherited maternal HLA-DRB1 antigen coding alleles as rheumatoid arthritis risk factors.BMC proceedings · 2007Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIt has recently been observed that non-inherited maternal DR4 antigens (NIMAs) of DR4 negative rheumatoid arthritis (RA) patients were increased compared with non-inherited paternal DR4 antigens (NIPAs). The aim of this study was to determine the prevalence of non-inherited DR4 antigens and DRB1 alleles in parents of RA patients.
methodsHLA-DR serology and DRB1 typing was performed in 97 RA patients and their parents. NIMA and NIPA frequencies were compared, stratified according to the presence of DR4 and/or the shared epitope (SE).
resultsIn DR4 negative patients, NIMA DR4 was increased compared with NIPA DR4 (OR 3.10, 95% CI 0.76, 12.70). When combined with results from a previous study this increase was significant (OR 3.65, 95% CI 1.29, 10.31). The NIMA effect of SE positive DR4 subtypes in this study (OR 4.73, 95% CI 0.94, 23.8) was stronger than the NIMA effect of combined SE positive DRB1 alleles (OR 2.19 95% CI 0.36, 13.22).
conclusionsThe association between non-inherited maternal HLA-DR4 alleles and the susceptibility to RA was observed in two independent populations.
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