ArticleBiophysical journal1999
Probabilistic modeling of shear-induced formation and breakage of doublets cross-linked by receptor-ligand bonds.
Article in Biophysical journal, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 65 citations in OpenAlex.
- Mechanical Model for Catch-Bond-Mediated Cell Adhesion in Shear Flow.International journal of molecular sciences · 2020Article
- A model for single-substrate trimolecular enzymatic kinetics.Biophysical journal · 2010Article
- Application of Population Dynamics to Study Heterotypic Cell Aggregations in the Near-Wall Region of a Shear Flow.Cellular and molecular bioengineering · 2010Article
- Lifetime and strength of periodic bond clusters between elastic media under inclined loading.Biophysical journal · 2009Article
- A hybrid computational model for phagocyte transmigration.Proceedings. IEEE International Symposium on Bioinformatics and Bioengineering · 2008Article
- Platelet adhesive dynamics. Part I: characterization of platelet hydrodynamic collisions and wall effects.Biophysical journal · 2008Article
- Two-dimensional kinetics of beta 2-integrin and ICAM-1 bindings between neutrophils and melanoma cells in a shear flow.American journal of physiology. Cell physiology · 2008Article
- Enhancement of L-selectin, but not P-selectin, bond formation frequency by convective flow.Biophysical journal · 2008Article
- Similarities between heterophilic and homophilic cadherin adhesion.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Flow-enhanced adhesion regulated by a selectin interdomain hinge.The Journal of cell biology · 2006Article
- Probabilistic modeling of rosette formation.Biophysical journal · 2006Article
- Biomechanics of P-selectin PSGL-1 bonds: shear threshold and integrin-independent cell adhesion.Biophysical journal · 2006Article
- Mechanics of transient platelet adhesion to von Willebrand factor under flow.Biophysical journal · 2005Article
- Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stress.Biophysical journal · 2004Article
- Dynamics of neutrophil aggregation in couette flow revealed by videomicroscopy: effect of shear rate on two-body collision efficiency and doublet lifetime.Biophysical journal · 2001Article
- Modeling concurrent binding of multiple molecular species in cell adhesion.Biophysical journal · 2000Article
- Analysis of competition binding between soluble and membrane-bound ligands for cell surface receptors.Biophysical journal · 1999Article
- Monte Carlo simulation of the heterotypic aggregation kinetics of platelets and neutrophils.Biophysical journal · 1999Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
A model was constructed to describe previously published experiments of shear-induced formation and breakage of doublets of red cells and of latexes cross-linked by receptor-ligand bonds (. Biophys. J. 65:1318-1334; Tees and Goldsmith. 1996. Biophys. J. 71:1102-1114;. Biophys. J. 71:1115-1122). The model, based on McQuarrie's master equations (1963. J. Phys. Chem. 38:433-436), provides unifying treatments for three distinctive time periods in the experiments of particles in a Couette flow in which a doublet undergoes 1) formation upon two-body collision between singlets; 2) evolution of bonds at low shear rate; and 3) break-up at high shear rate. Neglecting the applied force at low shear rate, the probability of forming a doublet per collision as well as the evolution of probability distribution of bonds in a preformed doublet were solved analytically and found to be in quite good agreement with measurements. At high shear rate with significant force acting to accelerate bond dissociation, the predictions for break-up of doublets were obtained numerically and compared well with data in both individual and population studies. These comparisons enabled bond kinetic parameters for three types of particles cross-linked by two receptor-ligand systems to be calculated, which agreed well with those computed from Monte Carlo simulations. This work can be extended to analyze kinetics of receptor-ligand binding in cell aggregates, such as those of neutrophils and platelets in the circulation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.