ArticleProceedings of the National Academy of Sciences of the United States of America1999
Involvement of specific calmodulin isoforms in salicylic acid-independent activation of plant disease resistance responses.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
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Who cites it
83 citing papers in PubMed, 275 citations in OpenAlex.
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- The response of Petunia × atkinsiana 'Pegasus Special Burgundy Bicolor' to mechanical stress encompassing morphological changes as well as physiological and molecular factors.Scientific reports · 2025Article
- MENTOR: Multiplex Embedding of Networks for Team-Based Omics Research.bioRxiv : the preprint server for biology · 2024Article
- Positive roles of the CaMolecular plant pathology · 2024Article
- Calcium signaling: an emerging player in plant antiviral defense.Journal of experimental botany · 2024Article
- Transcriptome analysis of sugarcane reveals rapid defense response of SES208 to Xanthomonas albilineans in early infection.BMC plant biology · 2023Article
- The calcium connection: exploring the intricacies of calcium signaling in plant-microbe interactions.Frontiers in plant science · 2023Review
- Comparative transcriptome profiling reveals differential defense responses amongFrontiers in plant science · 2023Article
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- TaBln1, a member of the Blufensin family, negatively regulates wheat resistance to stripe rust by reducing Ca2+ influx.Plant physiology · 2022Article
- Plant Responses to Herbivory, Wounding, and Infection.International journal of molecular sciences · 2022Review
- Linkage QTL Mapping and Genome-Wide Association Study on Resistance in Chickpea toFrontiers in genetics · 2022Article
- Quantitative Phosphoproteomics ofGenes · 2021Article
- Genome-wide approaches for the identification of markers and genes associated with sugarcane yellow leaf virus resistance.Scientific reports · 2021Article
- TypiCal but DeliCate CaFrontiers in plant science · 2021Review
- A TMT-Based Quantitative Proteome Analysis to Elucidate the TSWV Induced Signaling Cascade in Susceptible and Resistant Cultivars ofPlants (Basel, Switzerland) · 2020Article
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- CaFrontiers in plant science · 2020Review
23 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Ca2+ signal is essential for the activation of plant defense responses, but downstream components of the signaling pathway are still poorly defined. Here we demonstrate that specific calmodulin (CaM) isoforms are activated by infection or pathogen-derived elicitors and participate in Ca2+-mediated induction of plant disease resistance responses. Soybean CaM (SCaM)-4 and SCaM-5 genes, which encode for divergent CaM isoforms, were induced within 30 min by a fungal elicitor or pathogen, whereas other SCaM genes encoding highly conserved CaM isoforms did not show such response. This pathogen-triggered induction of these genes specifically depended on the increase of intracellular Ca2+ level. Constitutive expression of SCaM-4 and SCaM-5 in transgenic tobacco plants triggered spontaneous induction of lesions and induces an array of systemic acquired resistance (SAR)-associated genes. Surprisingly, these transgenic plants have normal levels of endogenous salicylic acid (SA). Furthermore, coexpression of nahG gene did not block the induction of SAR-associated genes in these transgenic plants, indicating that SA is not involved in the SAR gene induction mediated by SCaM-4 or SCaM-5. The transgenic plants exhibit enhanced resistance to a wide spectrum of virulent and avirulent pathogens, including bacteria, fungi, and virus. These results suggest that specific CaM isoforms are components of a SA-independent signal transduction chain leading to disease resistance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.