ArticleMolecular and cellular biology1999
Fission yeast cdc24 is a replication factor C- and proliferating cell nuclear antigen-interacting factor essential for S-phase completion.
Article in Molecular and cellular biology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- The DNA Damage Repair Function of Fission Yeast CK1 Involves Targeting Arp8, a Subunit of the INO80 Chromatin Remodeling Complex.Molecular and cellular biology · 2024Article
- Cdc24 Is Essential for Long-range End Resection in the Repair of Double-stranded DNA Breaks.The Journal of biological chemistry · 2016Article
- Unwinding the functions of the Pif1 family helicases.DNA repair · 2010Review
- Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeast.Molecular and cellular biology · 2006Article
- Roles of Pif1-like helicases in the maintenance of genomic stability.Nucleic acids research · 2006Review
- Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.Nucleic acids research · 2005Article
- Mapping and mutation of the conserved DNA polymerase interaction motif (DPIM) located in the C-terminal domain of fission yeast DNA polymerase delta subunit Cdc27.BMC molecular biology · 2004Article
- Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeast.Nucleic acids research · 2004Article
- Genetics of lagging strand DNA synthesis and maturation in fission yeast: suppression analysis links the Dna2-Cdc24 complex to DNA polymerase delta.Nucleic acids research · 2004Article
- Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast.Molecular genetics and genomics : MGG · 2004Article
- Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding.Molecular biology of the cell · 2003Article
- Article
- The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phase.Nucleic acids research · 2002Article
- mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.Eukaryotic cell · 2002Article
- Transcriptional silencing in Saccharomyces cerevisiae and Schizosaccharomyces pombe.Nucleic acids research · 2002Review
- The 14-kDa dynein light chain-family protein Dlc1 is required for regular oscillatory nuclear movement and efficient recombination during meiotic prophase in fission yeast.Molecular biology of the cell · 2002Article
- Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.The EMBO journal · 2001Article
- DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination.Proceedings of the National Academy of Sciences of the United States of America · 2001Review
- Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion.Molecular and cellular biology · 2001Article
- DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts.The Biochemical journal · 2000Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
At the nonpermissive temperature the fission yeast cdc24-M38 mutant arrests in the cell cycle with incomplete DNA replication as indicated by pulsed-field gel electrophoresis. The cdc24(+) gene encodes a 501-amino-acid protein with no significant homology to any known proteins. The temperature-sensitive cdc24 mutant is effectively rescued by pcn1(+), rfc1(+) (a fission yeast homologue of RFC1), and hhp1(+), which encode the proliferating cell nuclear antigen (PCNA), the large subunit of replication factor C (RFC), and a casein kinase I involved in DNA damage repair, respectively. The Cdc24 protein binds PCNA and RFC1 in vivo, and the domains essential for Cdc24 function and for RFC1 and PCNA binding colocalize in the N-terminal two-thirds of the molecule. In addition, cdc24(+) genetically interacts with the gene encoding the catalytic subunit of DNA polymerase epsilon, which is stimulated by PCNA and RFC, and with those encoding the fission yeast counterparts of Mcm2, Mcm4, and Mcm10. These results indicate that Cdc24 is an RFC- and PCNA-interacting factor required for DNA replication and might serve as a target for regulation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.