Evidence map›Paper›PMID 9889211›Full record

ArticleJournal of clinical microbiology1999

Identification of Candida dubliniensis in a prospective study of patients in the United States.

M A Jabra-Rizk, A A Baqui, J I Kelley, W A Falkler, W G Merz, T F Meiller

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 107 citations in OpenAlex.

  1. Review
  2. Article
  3. Candida dubliniensis endophthalmitis: five cases over 15 years.Journal of ophthalmic inflammation and infection · 2013
    Article
  4. Article
  5. Review
  6. Identification of Candida spp. by phenotypic tests and PCR.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2010
    Article
  7. Article
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  15. Review
  16. Article
  17. Article
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  19. Article
  20. Candida dubliniensis infection, Singapore.Emerging infectious diseases · 2002
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

M A Jabra-RizkDepartment of Oral Medicine, Dental School, University of Maryland, Baltimore 21201, USA. mrizk@umaryland.edu
A A Baqui
J I Kelley
W A Falkler
W G Merz
T F Meiller
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although Candida albicans remains the fungal species most frequently isolated as an opportunistic oral pathogen, other yeast species are often identified in human immunodeficiency virus (HIV)-seropositive patients. Candida dubliniensis phenotypically resembles C. albicans in many respects, yet it can be identified and differentiated as a unique Candida species by its phenotypic and genetic profiles. The purpose of the present study was to prospectively test for the presence of C. dubliniensis among clinical isolates and to determine the clinical and demographic characteristics of patients harboring C. dubliniensis. Over a 90-day period, isolates from 724 patients that were presumptively identified as C. albicans were screened for C. dubliniensis by use of tests for germ tube and chlamydospore production, by detection of an inability to grow at 45 degrees C, by colony color on CHROMagar Candida medium, and by the results of a sugar assimilation test with the API 20C AUX yeast identification system. Among 699 isolates retrieved from those specimens evaluated, 5 from 25 HIV-seropositive patients and 1 isolate from a patient whose HIV status was unknown were shown to be consistent by phenotyping and by electrophoretic karyotyping with the European reference strain of C. dubliniensis. One of the C. dubliniensis isolates had dose-dependent susceptibility to fluconazole (MIC, 16 microg/ml). These results confirm the presence of this interesting species in the United States and support the need for further investigations into the prevalence and pathogenesis of C. dubliniensis.

Indexed as

AdultAIDS-Related Opportunistic InfectionsAntifungal AgentsCandidaCandidiasis, OralCulture MediaElectrophoresis, Gel, Pulsed-FieldFemaleFluconazoleHIV SeropositivityHumansKaryotypingMaleMicrobial Sensitivity TestsMiddle AgedPhenotypeAntifungal AgentsCulture MediaFluconazole

Identifiers

PMID9889211
PMCPMC84296
OpenAlexW2170973729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.