ReviewThe Biochemical journal1999
Receptor-activated Ca2+ inflow in animal cells: a variety of pathways tailored to meet different intracellular Ca2+ signalling requirements.
Review in The Biochemical journal, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
67 citing papers in PubMed.
- Neuronal Store-Operated Calcium Channels.Molecular neurobiology · 2023Review
- Safranal Induces Vasorelaxation by Inhibiting CaMolecules (Basel, Switzerland) · 2022Article
- MRTF-A regulates CaJournal of biosciences · 2021Article
- Agonist-induced functional analysis and cell sorting associated with single-cell transcriptomics characterizes cell subtypes in normal and pathological brain.Genome research · 2020Article
- Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy.EMBO molecular medicine · 2020Article
- 3-Iodothyronamine Activates a Set of Membrane Proteins in Murine Hypothalamic Cell Lines.Frontiers in endocrinology · 2018Article
- Neurological and Motor Disorders: Neuronal Store-Operated CaAdvances in experimental medicine and biology · 2017Review
- Recent advances in the study of (-)clausenamide: chemistry, biological activities and mechanism of action.Acta pharmaceutica Sinica. B · 2014Review
- Role of calcium channels responsible for phenylephrine-induced contraction in rat aorta 3 days after acute myocardial infarction.Korean journal of anesthesiology · 2014Article
- Zinc inhibits osteoclast differentiation by suppression of Ca2+-Calcineurin-NFATc1 signaling pathway.Cell communication and signaling : CCS · 2013Article
- Pharmacological approaches to regulate neutrophil activity.Seminars in immunopathology · 2013Review
- Cch1 and Mid1 are functionally required for vegetative growth under low-calcium conditions in the phytopathogenic ascomycete Botrytis cinerea.Eukaryotic cell · 2013Article
- Ca(2+) homeostasis and regulation of ER Ca(2+) in mammalian oocytes/eggs.Cell calcium · 2013Review
- STIM/Orai signalling complexes in vascular smooth muscle.The Journal of physiology · 2012Review
- Effects and mechanisms of store-operated calcium channel blockade on hepatic ischemia-reperfusion injury in rats.World journal of gastroenterology · 2012Article
- TRPC channels in smooth muscle cells.Frontiers in bioscience (Landmark edition) · 2010Review
- Interplay between calcium and reactive oxygen/nitrogen species: an essential paradigm for vascular smooth muscle signaling.Antioxidants & redox signaling · 2010Review
- TRPC1 and STIM1 mediate capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells.The Journal of physiology · 2009Article
- Activation of phosphatidylinositol-linked novel D1 dopamine receptor contributes to the calcium mobilization in cultured rat prefrontal cortical astrocytes.Cellular and molecular neurobiology · 2009Article
- Complex functions of phosphatidylinositol 4,5-bisphosphate in regulation of TRPC5 cation channels.Pflugers Archiv : European journal of physiology · 2009Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Receptor-activated Ca2+ channels (RACCs) play a central role in regulation of the functions of animal cells. Together with voltage-operated Ca2+ channels (VOCCs) and ligand-gated non-selective cation channels, RACCs provide a variety of pathways by which Ca2+ can be delivered to the cytoplasmic space and the endoplasmic reticulum (ER) in order to initiate or maintain specific types of intracellular Ca2+ signal. Store-operated Ca2+ channels (SOCs), which are activated by a decrease in Ca2+ in the ER, are a major subfamily of RACCs. A careful analysis of the available data is required in order to discern the different types of RACCs (differentiated chiefly on the basis of ion selectivity and mechanism of activation) and to properly develop hypotheses for structures and mechanisms of activation. Despite much intensive research, the structures and mechanisms of activation of RACCs are only now beginning to be understood. In considering the physiological functions of the different RACCs, it is useful to consider the specificity for Ca2+ of each type of cation channel and the rate at which Ca2+ flows through a single open channel; the locations of the channels on the plasma membrane (in relation to the ER, cytoskeleton and other intracellular units of structure and function); the Ca2+-responsive enzymes and proteins; and the intracellular buffers and proteins that control the distribution of Ca2+ in the cytoplasmic space. RACCs which are non-selective cation channels can deliver Ca2+ directly to specific regions of the cytoplasmic space, and can also admit Na+, which induces depolarization of the plasma membrane, the opening of VOCCs and the subsequent inflow of Ca2+. SOCs appear to deliver Ca2+ specifically to the ER, thereby maintaining oscillating Ca2+ signals.
Indexed as
Identifiers
9882611PMC1219948What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.