ArticleJournal of bacteriology1999
Two distinct mechanisms cause heterogeneity of 16S rRNA.
Article in Journal of bacteriology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
45 citing papers in PubMed, 155 citations in OpenAlex.
- Orthogonal translation enables heterologous ribosome engineering in E. coli.Nature communications · 2021Article
- Molecular Identification and Antimicrobial Potential ofInternational journal of microbiology · 2020Article
- Comparative RNA function analysis reveals high functional similarity between distantly related bacterial 16 S rRNAs.Scientific reports · 2017Article
- Phylogenetic Network Analysis Revealed the Occurrence of Horizontal Gene Transfer of 16S rRNA in the GenusFrontiers in microbiology · 2017Article
- Highly divergent 16S rRNA sequences in ribosomal operons of Scytonema hyalinum (Cyanobacteria).PloS one · 2017Article
- Intra-Genomic Heterogeneity in 16S rRNA Genes in Strictly Anaerobic Clinical Isolates from Periodontal Abscesses.PloS one · 2015Article
- Description of an unusual Neisseria meningitidis isolate containing and expressing Neisseria gonorrhoeae-Specific 16S rRNA gene sequences.Journal of clinical microbiology · 2013Article
- Pre-sporulation stages of Streptomyces differentiation: state-of-the-art and future perspectives.FEMS microbiology letters · 2013Review
- Application of multilocus sequence analysis (MLSA) for accurate identification of Legionella spp. Isolated from municipal fountains in Chengdu, China, based on 16S rRNA, mip, and rpoB genes.Journal of microbiology (Seoul, Korea) · 2012Article
- 16S rRNA gene-based identification of bacteria in postoperative endophthalmitis by PCR-Denaturing Gradient Gel Electrophoresis (PCR-DGGE) fingerprinting.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2012Article
- New insights on the development ofCurrent trends in microbiology · 2012Article
- Article
- Core gene set as the basis of multilocus sequence analysis of the subclass Actinobacteridae.PloS one · 2011Article
- Article
- Characterization of heterogeneous LSU rRNA profiles in Streptomyces coelicolor under different growth stages and conditions.Current microbiology · 2008Article
- Molecular and phenotypic comparison of phaeochromycin-producing strains of Streptomyces phaeochromogenes and Streptomyces ederensis.Journal of industrial microbiology & biotechnology · 2008Article
- Population densities and genetic diversity of actinomycetes associated to the rhizosphere of Theobroma cacao.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2008Article
- Is 16S rDNA a reliable phylogenetic marker to characterize relationships below the family level in the enterobacteriaceae?Journal of molecular evolution · 2008Article
- Prevalence of lysogeny among soil bacteria and presence of 16S rRNA and trzN genes in viral-community DNA.Applied and environmental microbiology · 2008Article
- Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum.Microbiology and molecular biology reviews : MMBR · 2007Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the frequency of heterogeneity among the multiple 16S rRNA genes within a single microorganism, we determined directly the 120-bp nucleotide sequences containing the hypervariable alpha region of the 16S rRNA gene from 475 Streptomyces strains. Display of the direct sequencing patterns revealed the existence of 136 heterogeneous loci among a total of 33 strains. The heterogeneous loci were detected only in the stem region designated helix 10. All of the substitutions conserved the relevant secondary structure. The 33 strains were divided into two groups: one group, including 22 strains, had less than two heterogeneous bases; the other group, including 11 strains, had five or more heterogeneous bases. The two groups were different in their combinations of heterogeneous bases. The former mainly contained transitional substitutions, and the latter was mainly composed of transversional substitutions, suggesting that at least two mechanisms, possibly misincorporation during DNA replication and horizontal gene transfer, cause rRNA heterogeneity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.