Evidence map›Paper›PMID 9864256›Full record

ArticleInfection and immunity1999

Identification and functional characterization of the Neisseria gonorrhoeae lbpB gene product.

G D Biswas, J E Anderson, C J Chen, C N Cornelissen, P F Sparling

Abstract read
In one paragraph

Article in Infection and immunity, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Genomic analysis ofMicrobiology spectrum · 2026
    Article
  2. Article
  3. Review
  4. Clinical microbiology reviews · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Stealthy microbes: HowFrontiers in cellular and infection microbiology · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Biological Functions of the Secretome ofFrontiers in cellular and infection microbiology · 2017
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

G D BiswasDepartment of Medicine, School of Medicine, University of North Carolina at Chapel Hill 27599, USA. gdbis@med.unc.edu
J E Anderson
C J Chen
C N Cornelissen
P F Sparling

Funding

Trichomonas Typing SystemU19AI031496 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SPARLING, PHILIP FREDERICK · 1995 to 2014
$24.9M
LACTOFERRIN RECEPTOR AND GONOCOCCAL PATHOGENESISR01AI026837 · NIAID · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI SPARLING, PHILIP FREDERICK · 1999 to 2003
$1.4M
GENETICS AND BIOLOGY OF GONOCOCCAL PROTEIN IR37AI026837 · NIAID · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI SPARLING, PHILIP FREDERICK · 1988 to 1997
–
THE EPIDEMIOLOGY OF STDS IN RURAL NORTH CAROLINAU01AI031496 · NIAID · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI SPARLING, PHILIP FREDERICK · 1991 to 1994
–
NIAID NIH HHS AI26837NIAID NIH HHS AI31496NIAID NIH HHS R01 AI026837NIAID NIH HHS R37 AI026837NIAID NIH HHS U19 AI031496
6 · The paper itself

Abstract

We cloned lbpB, encoding a predicted 80-kDa lipoprotein, upstream of lbpA. A nonpolar mutant (LbpB- LbpA+) had normal lactoferrin (LF) binding and grew normally with LF as an iron source, whereas LbpB- LbpA- and LbpB+ LbpA- strains had reduced binding of LF and did not grow with LF as an iron source. LbpB bound LF directly in an affinity purification, suggesting that LbpB might play a still-uncharacterized role in the LF iron utilization.

Indexed as

Amino Acid SequenceBacterial Outer Membrane ProteinsChromatography, AffinityCloning, MolecularGenes, BacterialIronLactoferrinMolecular Sequence DataNeisseria gonorrhoeaeReceptors, Cell SurfaceBacterial Outer Membrane ProteinsIronLactoferrinLBPA protein, Neisseria meningitidisReceptors, Cell Surface

Identifiers

PMID9864256
PMCPMC96337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.