ArticleVirus genes1998
Envelope and long terminal repeat sequences of an infectious murine leukemia virus from a human SCLC cell line: implications for gene transfer.
Article in Virus genes, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Characterization, mapping, and distribution of the two XMRV parental proviruses.Journal of virology · 2012Article
- The human lung adenocarcinoma cell line EKVX produces an infectious xenotropic murine leukemia virus.Viruses · 2011Article
- Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts.Cancer biology & therapy · 2011Article
- Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant.PLoS pathogens · 2006Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Development of methods for gene transfer into specific cell types or tissues is important for experimental research as well as clinical therapeutical approaches. We report here the cloning and characterization of the envelope (env) gene and the U3 region of a retrovirus from an infected human Small Cell Lung Cancer (SCLC) cell line. The replication of this murine retrovirus is also fully supported by other lung cancer cell lines of different histological origin. We present evidence that a long terminal repeat (LTR)-beta-galactosidase (beta-Gal) reporter construct performed as well as an analogous cytomegalovirus (CMV) promoter beta-Gal construct in the human lung epithelial cell line A549 and in the human larynx carcinoma cell line HEp2.
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