ArticleGenes & development1998
Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1.
Article in Genes & development, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 535 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
535 citing papers in PubMed, 1,269 citations in OpenAlex.
- Article
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- Direct avirulence effector-receptor interaction confers wheat immunity against insects.Science advances · 2026Article
- Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026Review
- Rice adaptation to low-light stress: integrating morpho-physiology, biochemical plasticity, signalling networks and molecular breeding strategies.Plant cell reports · 2026Review
- Integrated morpho-physiological, metabolomic and transcriptomic profiling uncovers ethylene-mediated metabolic regulation shaping drought resilience in wheat.BMC plant biology · 2026Article
- 14-3-3 λ suppresses ethylene-mediated root growth inhibition through EIN3/EIL1 in Aratbidopsis.Plant physiology · 2026Article
- Under heavy metal stress: genomic characterization and expression profiles of miRNA families in Phaseolus vulgaris.BMC plant biology · 2026Article
- Article
- The core clock transcription factor TOC1 binds directly to defence gene promoters regulating immunity in Arabidopsis.Communications biology · 2026Article
- The importin-alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus.The FEBS journal · 2026Article
- Sex-specific ethylene responses drive floral sexual plasticity in Cannabis sativa.The Plant journal : for cell and molecular biology · 2026Article
- EBSn, a Robust Synthetic Reporter for Monitoring Ethylene Responses in Plants.Plant biotechnology journal · 2026Article
- Transcription Factor PFB1 Is Required for the Botrytis cinerea Effector BcSCR1-Mediated Pathogenesis.Molecular plant pathology · 2026Article
- Ethylene represses jasmonate signaling to attenuate nicotine biosynthesis inFrontiers in plant science · 2026Article
- Genome-wide analysis of theFrontiers in plant science · 2026Article
- Genome-wide identification, characterization and expression profiling of purple acid phosphatases under variable phosphorus regimes in lentil (Lens culinaris Medik.).BMC plant biology · 2025Article
- An Ethylene-Response Factor LlERF092 Coordinates With LlETO1 to Improve Thermotolerance by Activating LlMBF1c in Lily.Plant biotechnology journal · 2025Article
- Co-domestication of cold tolerance and female flower is determined by CsEIN2 in cucumber.Plant biotechnology journal · 2025Article
- Analysis of the AP2/ERF transcription factor family in Eriobotrya japonica and its role in exogenous melatonin-mediated regulation of salt stress.Functional & integrative genomics · 2025Article
475 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Response to the gaseous plant hormone ethylene in Arabidopsis requires the EIN3/EIL family of nuclear proteins. The biochemical function(s) of EIN3/EIL proteins, however, has remained unknown. In this study, we show that EIN3 and EILs comprise a family of novel sequence-specific DNA-binding proteins that regulate gene expression by binding directly to a primary ethylene response element (PERE) related to the tomato E4-element. Moreover, we identified an immediate target of EIN3, ETHYLENE-RESPONSE-FACTOR1 (ERF1), which contains this element in its promoter. EIN3 is necessary and sufficient for ERF1 expression, and, like EIN3-overexpression in transgenic plants, constitutive expression of ERF1 results in the activation of a variety of ethylene response genes and phenotypes. Evidence is also provided that ERF1 acts downstream of EIN3 and all other components of the ethylene signaling pathway. The results demonstrate that the nuclear proteins EIN3 and ERF1 act sequentially in a cascade of transcriptional regulation initiated by ethylene gas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.