ArticlePlant physiology1998
Role of the ascorbate-glutathione cycle of mitochondria and peroxisomes in the senescence of pea leaves
Article in Plant physiology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 374 citations in OpenAlex.
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- Light Intensity- and Spectrum-Dependent Redox Regulation of Plant Metabolism.Antioxidants (Basel, Switzerland) · 2022Review
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- Is Autophagy Involved in Pepper Fruit Ripening?Cells · 2020Article
- Plant Peroxisomes: A Factory of Reactive Species.Frontiers in plant science · 2020Review
- PtomtAPX, a mitochondrial ascorbate peroxidase, plays an important role in maintaining the redox balance of Populus tomentosa Carr.Scientific reports · 2019Article
- iTRAQ-Based Comparative Proteomic Analysis of the Roots of TWO Winter Turnip Rapes (International journal of molecular sciences · 2018Article
- Exogenous salicylic acid regulates reactive oxygen species metabolism and ascorbate-glutathione cycle inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2018Article
- Reproductive sink enhanced drought induced senescence in wheat fertile line is associated with loss of antioxidant competence compared to its CMS line.Physiology and molecular biology of plants : an international journal of functional plant biology · 2018Article
- The role of silver ions in the regulation of the senescence process in Triticum aestivum.Turkish journal of biology = Turk biyoloji dergisi · 2018Article
- A Central Role for Triacylglycerol in Membrane Lipid Breakdown, Fatty AcidPlant physiology · 2017Article
- Sexual Dimorphism in the Response of Mercurialis annua to Stress.Metabolites · 2016Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the relationship between H2O2 metabolism and the senescence process using soluble fractions, mitochondria, and peroxisomes from senescent pea (Pisum sativum L.) leaves. After 11 d of senescence the activities of Mn-superoxide dismutase, dehydroascorbate reductase (DHAR), and glutathione reductase (GR) present in the matrix, and ascorbate peroxidase (APX) and monodehydroascorbate reductase (MDHAR) activities localized in the mitochondrial membrane, were all substantially decreased in mitochondria. The mitochondrial ascorbate and dehydroascorbate pools were reduced, whereas the oxidized glutathione levels were maintained. In senescent leaves the H2O2 content in isolated mitochondria and the NADH- and succinate-dependent production of superoxide (O2.-) radicals by submitochondrial particles increased significantly. However, in peroxisomes from senescent leaves both membrane-bound APX and MDHAR activities were reduced. In the matrix the DHAR activity was enhanced and the GR activity remained unchanged. As a result of senescence, the reduced and the oxidized glutathione pools were considerably increased in peroxisomes. A large increase in the glutathione pool and DHAR activity were also found in soluble fractions of senescent pea leaves, together with a decrease in GR, APX, and MDHAR activities. The differential response to senescence of the mitochondrial and peroxisomal ascorbate-glutathione cycle suggests that mitochondria could be affected by oxidative damage earlier than peroxisomes, which may participate in the cellular oxidative mechanism of leaf senescence longer than mitochondria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.