ArticleThe Plant cell1998
Chloroplast division in higher plants requires members of two functionally divergent gene families with homology to bacterial ftsZ.
Article in The Plant cell, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.
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Who cites it
122 citing papers in PubMed, 354 citations in OpenAlex.
- Plant organelle division orchestrated by the mosaic machinery of endosymbiotic relics and eukaryotic host factors.Plant physiology · 2026Review
- Dual Cytoplasmic and Chloroplastic Mechanisms Fine-Tune Chloroplast Division through ARC3 Protein Stability.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Binary division of plastids involves endoplasmic reticulum mediation.Journal of experimental botany · 2025Article
- Optimal disk packing of chloroplasts in plant cells.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Filamentous Temperature-Sensitive Z Protein J175 Regulates Maize Chloroplasts' and Amyloplasts' Division and Development.Plants (Basel, Switzerland) · 2025Article
- Enhanced chloroplast FtsZ-ring constriction by the ARC6-ARC3 module inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins.Scientific reports · 2025Article
- Chloroplast Z-ring dynamics is governed by conserved core regions of evolutionarily divergent FtsZs.Frontiers in plant science · 2025Article
- Principles of amyloplast replication in the ovule integuments of Arabidopsis thaliana.Plant physiology · 2024Article
- Genome-Editing ofPlants (Basel, Switzerland) · 2023Article
- Comparative physiology and transcriptome analysis reveals that chloroplast development influences silver-white leaf color formation in Hydrangea macrophylla var. maculata.BMC plant biology · 2022Article
- Coordination mechanism of cell and cyanelle division in the glaucophyte alga Cyanophora sudae.Protoplasma · 2022Article
- WHIRLY1 functions in the nucleus to regulate barley leaf development and associated metabolite profiles.The Biochemical journal · 2022Article
- A novel amphiphilic motif at the C-terminus of FtsZ1 facilitates chloroplast division.The Plant cell · 2022Article
- Mutation of SlARC6 leads to tissue-specific defects in chloroplast development in tomato.Horticulture research · 2021Article
- Genome-Wide Analysis of Tubulin Gene Family in Cassava and Expression of Family MemberPlants (Basel, Switzerland) · 2021Article
- Challenges and Approaches to Crop Improvement Through C3-to-C4 Engineering.Frontiers in plant science · 2021Review
- Generation, analysis, and transformation of macro-chloroplast Potato (Solanum tuberosum) lines for chloroplast biotechnology.Scientific reports · 2020Article
- Behavior of filamentous temperature-sensitive Z2 (FtsZ2) in the male gametophyte during sexual reproduction processes of flowering plants.Protoplasma · 2020Article
- A NanoFE simulation-based surrogate machine learning model to predict mechanical functionality of protein networks from live confocal imaging.Computational and structural biotechnology journal · 2020Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The division of plastids is critical for viability in photosynthetic eukaryotes, but the mechanisms associated with this process are still poorly understood. We previously identified a nuclear gene from Arabidopsis encoding a chloroplast-localized homolog of the bacterial cell division protein FtsZ, an essential cytoskeletal component of the prokaryotic cell division apparatus. Here, we report the identification of a second nuclear-encoded FtsZ-type protein from Arabidopsis that does not contain a chloroplast targeting sequence or other obvious sorting signals and is not imported into isolated chloroplasts, which strongly suggests that it is localized in the cytosol. We further demonstrate using antisense technology that inhibiting expression of either Arabidopsis FtsZ gene (AtFtsZ1-1 or AtFtsZ2-1) in transgenic plants reduces the number of chloroplasts in mature leaf cells from 100 to one, indicating that both genes are essential for division of higher plant chloroplasts but that each plays a distinct role in the process. Analysis of currently available plant FtsZ sequences further suggests that two functionally divergent FtsZ gene families encoding differentially localized products participate in chloroplast division. Our results provide evidence that both chloroplastic and cytosolic forms of FtsZ are involved in chloroplast division in higher plants and imply that important differences exist between chloroplasts and prokaryotes with regard to the roles played by FtsZ proteins in the division process.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.