ArticlePharmaceutical research1998
Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.
Article in Pharmaceutical research, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Misconceptions among medicinal chemists regarding ADME and PK optimization.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026Article
- PBBM Considerations for Base Models, Model Validation, and Application Steps: Workshop Summary Report.Molecular pharmaceutics · 2024Review
- Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus.Drug delivery and translational research · 2024Article
- Prediction of Oral Drug Absorption in Rats from In Vitro Data.Pharmaceutical research · 2023Article
- The Effect of Anesthetic Regimens on Intestinal Absorption of Passively Absorbed Drugs in Rats.Pharmaceutical research · 2020Article
- Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats.Frontiers in pharmacology · 2020Article
- LC478, a Novel Di-Substituted Adamantyl Derivative, Enhances the Oral Bioavailability of Docetaxel in Rats.Pharmaceutics · 2019Article
- Synergistic Effect of ZnO Nanoparticles and Carbon Nanotube and Polymeric Film on Electrochemical Oxidation of Acyclovir.Iranian journal of pharmaceutical research : IJPR · 2018Article
- Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.Biopharmaceutics & drug disposition · 2017Review
- Physiologically Based Absorption Modeling to Design Extended-Release Clinical Products for an Ester Prodrug.The AAPS journal · 2016Article
- Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.Clinical pharmacokinetics · 2016Review
- Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.The AAPS journal · 2016Review
- Intestinal absorption characteristics of imperialine: in vitro and in situ assessments.Acta pharmacologica Sinica · 2015Article
- Article
- Animal versus human oral drug bioavailability: do they correlate?European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2014Article
- The use of ROC analysis for the qualitative prediction of human oral bioavailability from animal data.Pharmaceutical research · 2014Article
- Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake.International journal of nanomedicine · 2014Article
- Curcumin Regulates Colon Cancer by Inhibiting P-Glycoprotein inJournal of cancer science & therapy · 2013Article
- PXR/CYP3A4-humanized mice for studying drug-drug interactions involving intestinal P-glycoprotein.Molecular pharmaceutics · 2013Article
- Interspecies modeling and prediction of human exenatide pharmacokinetics.Pharmaceutical research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
9834005What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.