ArticleGenetics1998
Extraordinary ribosomal spacer length heterogeneity in a neotyphodium endophyte hybrid: implications for concerted evolution.
Article in Genetics, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 61 citations in OpenAlex.
- Article
- Article
- Comparative genetic analysis of the 45S rDNA intergenic spacers from three Saccharum species.PloS one · 2017Article
- Genetic and Biochemical Characterization of Monokaryotic Progeny Strains of Button Mushroom (Agaricus bisporus).Mycobiology · 2015Article
- An interspecific fungal hybrid reveals cross-kingdom rules for allopolyploid gene expression patterns.PLoS genetics · 2014Article
- Characterization of the intergenic spacer rDNAs of two pig nodule worms, Oesophagostomum dentatum and O. quadrispinulatum.TheScientificWorldJournal · 2014Article
- The IGS-ETS in Bacillus (Insecta Phasmida): molecular characterization and the relevance of sex in ribosomal DNA evolution.BMC evolutionary biology · 2008Article
- High-frequency intragenomic heterogeneity of the ribosomal DNA intergenic spacer region in Trichophyton violaceum.Eukaryotic cell · 2008Article
- Patterns of concerted evolution of the rDNA family in a natural population of Zhikong scallop, Chlamys farreri.Journal of molecular evolution · 2007Article
- Highly efficient concerted evolution in the ribosomal DNA repeats: total rDNA repeat variation revealed by whole-genome shotgun sequence data.Genome research · 2007Article
- Identifying gene-independent noncoding functional elements in the yeast ribosomal DNA by phylogenetic footprinting.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Functional and ecological significance of rDNA intergenic spacer variation in a clonal organism under divergent selection for production rate.Proceedings. Biological sciences · 2002Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An extraordinary level of length heterogeneity was found in the ribosomal DNA (rDNA) of an asexual hybrid Neotyphodium grass endophyte, isolate Lp1. This hybrid Neotyphodium endophyte is an interspecific hybrid between two grass endophytes, Neotyphodium lolii, and a sexual form, Epichlöe typhina, and the length heterogeneity was not found in either of these progenitor species. The length heterogeneity in the hybrid is localized to the intergenic spacer (IGS) and is the result of copy-number variation of a tandemly repeated subrepeat class within the IGS, the 111-/119-bp subrepeats. Copy number variation of this subrepeat class appears to be a consequence of mitotic unequal crossing over that occurs between these subrepeats. This implies that unequal crossing over plays a role in the concerted evolution of the whole rDNA. Changes in the pattern of IGS length variants occurred in just two rounds of single-spore purification. Analysis of the IGS length heterogeneity revealed features that are unexpected in a simple model of unequal crossing over. Potential refinements of the molecular details of unequal crossing over are presented, and we also discuss evidence for a combination of homogenization mechanisms that drive the concerted evolution of the Lp1 rDNA.
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