ArticleBiophysical journal1998
Dynamic properties of Na+ ions in models of ion channels: a molecular dynamics study.
Article in Biophysical journal, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A Model Framework for Ion Channels with Selectivity Filters Based on Non-Equilibrium Thermodynamics.Entropy (Basel, Switzerland) · 2025Article
- Molecular Mean-Field Theory of Ionic Solutions: A Poisson-Nernst-Planck-Bikerman Model.Entropy (Basel, Switzerland) · 2020Review
- Measurements of the size and correlations between ions using an electrolytic point contact.Nature communications · 2019Article
- Singular perturbation analysis of the steady-state Poisson-Nernst-Planck system: Applications to ion channels.European journal of applied mathematics · 2008Article
- Ion transport through membrane-spanning nanopores studied by molecular dynamics simulations and continuum electrostatics calculations.Biophysical journal · 2005Article
- Water dynamics and dewetting transitions in the small mechanosensitive channel MscS.Biophysical journal · 2004Article
- OmpA: a pore or not a pore? Simulation and modeling studies.Biophysical journal · 2002Article
- The formation and dynamics of proton wires in channel environments.Biophysical journal · 2001Article
- Mechanisms of permeation and selectivity in calcium channels.Biophysical journal · 2001Article
- Three-dimensional Poisson-Nernst-Planck theory studies: influence of membrane electrostatics on gramicidin A channel conductance.Biophysical journal · 2000Article
- Permeation of ions across the potassium channel: Brownian dynamics studies.Biophysical journal · 1999Article
- Molecular dynamics study of the KcsA potassium channel.Biophysical journal · 1999Article
- Molecular dynamics of synthetic leucine-serine ion channels in a phospholipid membrane.Biophysical journal · 1999Article
- Modeling of ion channels.The Journal of general physiology · 1999Review
- An alamethicin channel in a lipid bilayer: molecular dynamics simulations.Biophysical journal · 1999Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
We present simulation results for the effective diffusion coefficients of a sodium ion in a series of model ion channels of different diameters and hydrophobicities, including models of alamethicin, a leucine-serine peptide, and the M2 helix bundle of the nicotinic acetylcholine receptor. The diffusion coefficient, which in the simulations has a value of 0.15(2) A2ps-1 in bulk water, is found to be reduced to as little as 0.02(1) A2ps-1 in the narrower channels, and to about 0.10(5) A2ps-1 in wider channels such as the nicotinic acetylcholine receptor. It is anticipated that this work will be useful in connection with calculations of channel conductivity using such techniques as the Poisson-Nernst-Planck equation, Eyring rate theory, or Brownian dynamics.
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