ReviewMolecular and cellular biochemistry1998
The molecular basis for the role of zinc in developmental biology.
Review in Molecular and cellular biochemistry, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 252 citations in OpenAlex.
- Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates.The Cochrane database of systematic reviews · 2021Pooled it
- Dual-mode NRSC advances · 2026Article
- Approximate size and preliminary composition of the low-mass zinc pool in the cytosol of Saccharomyces cerevisiae.The Journal of biological chemistry · 2026Article
- Article
- Maternal iron and zinc and preterm labor risk: A nested case-control study based on the Lanzhou Birth Cohort Study (BBCS) in China.Asia Pacific journal of clinical nutrition · 2025Article
- Zinc and Its Antioxidant Properties: The Potential Use of Blood Zinc Levels as a Marker of Cancer Risk in BRCA1 Mutation Carriers.Antioxidants (Basel, Switzerland) · 2024Article
- Correlation between Selenium and Zinc Levels and Survival among Prostate Cancer Patients.Nutrients · 2024Article
- Study of Serum Copper and Zinc Levels and Serum Cu/Zn Ratio among Polish Women with Endometrial Cancer.Nutrients · 2023Article
- Resolving the zinc binding capacity of honey bee vitellogenin and locating its putative binding sites.Insect molecular biology · 2022Article
- A quinazolin-based Schiff-base chemosensor for colorimetric detection of NiRSC advances · 2022Article
- Association of Zn and Cu Levels in Cord Blood and Maternal Milk with Pregnancy Outcomes among the Slovenian Population.Nutrients · 2022Article
- Zinc supplementation modifies brain tissue transcriptome of Apis mellifera honeybees.BMC genomics · 2022Article
- Multipurpose made colorimetric materials for amines, pH change and metal ion detection.RSC advances · 2022Article
- A Novel Imidazole Bound Schiff Base as Highly Selective "Turn-on" Fluorescence Sensor for ZnJournal of fluorescence · 2022Article
- Tris-(2-pyridyl)-pyrazolyl Borate Zinc(II) Complexes: Synthesis, DNA/Protein Binding and In Vitro Cytotoxicity Studies.Molecules (Basel, Switzerland) · 2021Article
- A Highly Selective Turn-On Fluorescent Probe for the Detection of Zinc.Molecules (Basel, Switzerland) · 2021Article
- The Scarcity of Specific Nutrients in Wild Bee Larval Food Negatively Influences Certain Life History Traits.Biology · 2020Article
- Energetic supplementation for maintenance or development ofThe journal of venomous animals and toxins including tropical diseases · 2020Article
- Synthesis and characterization of newly synthesized neodymium zirconate zinc sulfide nanocomposite and its effect on selected aspects of albino mice behavior.Naunyn-Schmiedeberg's archives of pharmacology · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinc regulates the gene expression machinery. It affects the structure of chromatin, the template function of its DNA, the activity of numerous transcription factors and of RNA polymerases. Hence, it determines both the types of mRNA transcripts synthesized and the rate of transcription itself. Alterations in one or more of these zinc dependent processes have been proposed to account for the proliferative arrest and teratology induced by zinc deficiency. To examine this proposal, studies of zinc during X. laevis development have been initiated. The kinetics of X. laevis oocyte zinc uptake and storage and of zinc utilization during embryogenesis have been examined first. Vitellogenin carries zinc into the oocyte. Ten % of the total zinc (10 ng/egg) remains within the cytosol while 90% (90 ng/egg) is stored in the yolk platelets associated with lipovitellin. The cytosolic pool is the source of the zinc for all newly formed metalloproteins involved in embryo development. The yolk platelet zinc pool is stored for later use during early metamorphosis. It is now possible to examine zinc transfer to molecules, such as e.g. transcription factors, and the role of the metal in their function in development and organogenesis.
Indexed as
Identifiers
9823009W1533404869What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.