ArticleProceedings. Biological sciences1998
Microparasite population dynamics and continuous immunity.
Article in Proceedings. Biological sciences, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Optimal vaccination policy to prevent endemicity: a stochastic model.Journal of mathematical biology · 2024Article
- An immuno-epidemiological model with waning immunity after infection or vaccination.Journal of mathematical biology · 2024Article
- Comparative reconstruction of SARS-CoV-2 transmission in three African countries using a mathematical model integrating immunity data.IJID regions · 2024Article
- Immuno-epidemiology of a population structured by immune status: a mathematical study of waning immunity and immune system boosting.Journal of mathematical biology · 2015Article
- Demographic buffering: titrating the effects of birth rate and imperfect immunity on epidemic dynamics.Journal of the Royal Society, Interface · 2015Article
- Rotavirus within day care centres in Oxfordshire, UK: characterization of partial immunity.Journal of the Royal Society, Interface · 2008Article
- Understanding the transmission dynamics of respiratory syncytial virus using multiple time series and nested models.Mathematical biosciences · 2007Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A mathematical model is presented for the transmission of a microparasite where the hosts occupy one of two states, uninfected or infected. In each state, the hosts are distributed over a continuous range of immunity. The immune levels vary within hosts due to the processes of waning of immunity (when uninfected), and increasing immunity (when infected), eventually resulting in recovery. Immunity level also influences the host's ability to infect or be infected. Thus the proposed model incorporates both inter- and intra-host dynamics. It is shown from equilibrium results that this model is a general form of the susceptible-infected-resistant (SIR) and susceptible-infected-susceptible (SIS) family of models, a development that is useful for exploring multistrain pathogen transmission and use of vaccines which confer temporary protection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.