Evidence map›Paper›PMID 9817898›Full record

ArticleJournal of clinical microbiology1998

Rapid PCR detection of Helicobacter pylori-associated virulence and resistance genes directly from gastric biopsy material.

B Björkholm, R Befrits, B Jaup, L Engstrand

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Molecular detection of antimicrobial resistance.Clinical microbiology reviews · 2001
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

B BjörkholmDepartment of Medicine, Karolinska Institute, Stockholm, Sweden.
R Befrits
B Jaup
L Engstrand

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have developed a PCR-based method to detect macrolide resistance and the virulence gene cagA in Helicobacter pylori within 24 h, thereby improving the lengthy process of culture-based approaches. Total DNA was prepared directly from stomach biopsy specimens. The procedure proved to be rapid and reliable and could be utilized for diagnostic purposes.

Indexed as

Antigens, BacterialGenes, BacterialPolymerase Chain ReactionBacterial ProteinsClarithromycinDrug Resistance, MicrobialHelicobacter pyloriHumansStomachVirulenceAntigens, BacterialBacterial ProteinscagA protein, Helicobacter pyloriClarithromycin

Identifiers

PMID9817898
PMCPMC105265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.