ReviewJournal of autism and developmental disorders1998
Autism: the point of view from fragile X studies.
Review in Journal of autism and developmental disorders, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 140 citations in OpenAlex.
- Using Zebrafish to Model Autism Spectrum Disorder: A Comparison of ASD Risk Genes Between Zebrafish and Their Mammalian Counterparts.Frontiers in molecular neuroscience · 2020Review
- Differentiating social preference and social anxiety phenotypes in fragile X syndrome using an eye gaze analysis: a pilot study.Journal of neurodevelopmental disorders · 2019Article
- Evaluating Sensory Processing in Fragile X Syndrome: Psychometric Analysis of the Brain Body Center Sensory Scales (BBCSS).Journal of autism and developmental disorders · 2018Article
- Do psychoactive drugs have a therapeutic role in compulsivity? Studies on schedule-induced polydipsia.Psychopharmacology · 2018Article
- Specificity: A Phenotypic Comparison of Communication-Relevant Domains Between Youth With Down Syndrome and Fragile X Syndrome.Frontiers in genetics · 2018Article
- Sensory processing in autism spectrum disorders and Fragile X syndrome-From the clinic to animal models.Neuroscience and biobehavioral reviews · 2017Review
- Change in the Behavioral Phenotype of Adolescents and Adults with FXS: Role of the Family Environment.Journal of autism and developmental disorders · 2016Article
- A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Frontiers in cellular neuroscience · 2016Review
- Do Children With Fragile X Syndrome Show Declines or Plateaus in Adaptive Behavior?American journal on intellectual and developmental disabilities · 2015Article
- Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder.Journal of autism and developmental disorders · 2015Article
- Symptoms of Autism in Males with Fragile X Syndrome: A Comparison to Nonsyndromic ASD Using Current ADI-R Scores.Journal of autism and developmental disorders · 2015Article
- Developing Medications Targeting Glutamatergic Dysfunction in Autism: Progress to Date.CNS drugs · 2015Review
- Auditory processing in fragile x syndrome.Frontiers in cellular neuroscience · 2014Review
- Investigating word learning in fragile X syndrome: a fast-mapping study.Journal of autism and developmental disorders · 2013Article
- Influences on maternal responsivity in mothers of children with fragile X syndrome.American journal on intellectual and developmental disabilities · 2013Article
- Evidence of a distinct behavioral phenotype in young boys with fragile X syndrome and autism.Journal of the American Academy of Child and Adolescent Psychiatry · 2012Article
- Profiles of receptive and expressive language abilities in boys with comorbid fragile X syndrome and autism.American journal on intellectual and developmental disabilities · 2012Article
- The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide.Behavioral neuroscience · 2011Article
- Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome.Psychopharmacology · 2011Article
- Altered zinc transport disrupts mitochondrial protein processing/import in fragile X-associated tremor/ataxia syndrome.Human molecular genetics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between the fragile X syndrome (FXS) and autism is reviewed. Shortly after the FXS was first described, it was noted that certain behaviors commonly found in afflicted individuals resemble certain features of autism. Research concerning a possible relationship between these conditions is summarized. The outcome of this research indicates that FXS is not a common cause of autism, although the number of individuals with FXS who meet diagnostic criteria for autism is higher than can be accounted for by chance. The major focus of this paper highlights that FXS is a well-defined neurogenetic disease that includes a cognitive behavioral phenotype, and has both a known biological cause and an increasing well-delineated pathogenesis. Autism is a behaviorally defined syndrome whose syndromic boundaries and biological causes are not known. These profound differences complicate comparisons and causal discussions. However, the behavioral neurogenetic information available about FXS suggests certain pathways for future research directed at elucidating the syndrome of autism.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.