Evidence map›Paper›PMID 9812778›Full record

ArticleJournal of Tongji Medical University = Tong ji yi ke da xue xue bao1997

The relationship between 67KD laminin receptor expression and metastasis of hepatocellular carcinoma.

S Zheng, Y Ruan, Z Wu, J Tang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

S ZhengDepartment of Ultrastructural Pathology, Research Center of Experimental Medicine, Tongji Medical University, Wuhan.
Y Ruan
Z Wu
J Tang
Tongji University · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 67KD laminin receptor (LN-R) that binds laminin (LN) is involved in the metastasis cascade. Using immunohistochemical technique, in situ hybridization and reverse transcription polymerase chain reaction (RT-PCR), we studied LN-R protein and RNA levels in 30 cases of human hepatocellular carcinoma (HCC) to further understand its role in the metastasis of HCC. In our 14 cases of HCC with metastasis, its positive rates were 71.4%, 57.1%, 85.7% respectively, whereas its positive expression in 16 cases without metastasis were 31.3%, 18.8%, 50.0% respectively. The significant difference was found between these two groups. The results suggest that the 67KD LN-R expression plays a very important role in the metastasis of HCC.

Indexed as

Basement MembraneCarcinoma, HepatocellularHumansImmunohistochemistryLiver NeoplasmsLymphatic MetastasisReceptors, LamininRNA, NeoplasmReceptors, LamininRNA, Neoplasm

Identifiers

PMID9812778
OpenAlexW2060124448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.