ArticleJournal of bacteriology1998
Autolysis of Lactococcus lactis is influenced by proteolysis.
Article in Journal of bacteriology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 70 citations in OpenAlex.
- Chromosomal and Plasmid-Based CRISPRi Platforms for Conditional Gene Silencing inInternational journal of molecular sciences · 2025Article
- Molecular typing and antimicrobial resistance profiling of 33 mastitis-related Staphylococcus aureus isolates from cows in the Comarca Lagunera region of Mexico.Scientific reports · 2021Article
- Expression of prophage-encoded endolysins contributes to autolysis of Lactococcus lactis.Applied microbiology and biotechnology · 2017Article
- Cell wall structure and function in lactic acid bacteria.Microbial cell factories · 2014Review
- Article
- Reduced lysis upon growth of Lactococcus lactis on galactose is a consequence of decreased binding of the autolysin AcmA.Applied and environmental microbiology · 2008Article
- Positive role of cell wall anchored proteinase PrtP in adhesion of lactococci.BMC microbiology · 2007Article
- Carbohydrate starvation causes a metabolically active but nonculturable state in Lactococcus lactis.Applied and environmental microbiology · 2007Article
- The atlA operon of Streptococcus mutans: role in autolysin maturation and cell surface biogenesis.Journal of bacteriology · 2006Article
- Autolysis of Lactococcus lactis is increased upon D-alanine depletion of peptidoglycan and lipoteichoic acids.Journal of bacteriology · 2005Article
- Effects of high pressure on the viability, morphology, lysis, and cell wall hydrolase activity of Lactococcus lactis subsp. cremoris.Applied and environmental microbiology · 2002Article
- Contribution of Lactococcus lactis cell envelope proteinase specificity to peptide accumulation and bitterness in reduced-fat Cheddar cheese.Applied and environmental microbiology · 2002Article
- Identification of Rgg-regulated exoproteins of Streptococcus pyogenes.Infection and immunity · 2001Article
- Requirement of autolytic activity for bacteriocin-induced lysis.Applied and environmental microbiology · 2000Article
- Expression of the Staphylococcus hyicus lipase in Lactococcus lactis.Applied and environmental microbiology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The autolysin AcmA of Lactococcus lactis was shown to be degraded by the extracellular lactococcal proteinase PrtP. Autolysis, as evidenced by reduction in optical density of a stationary-phase culture and concomitant release of intracellular proteins, was greatly reduced when L. lactis MG1363 cells expressed the cell wall-anchored lactococcal proteinase PrtP of the PI-type caseinolytic specificity (PI). On the other hand, lactococcal strains that did not produce the proteinase showed a high level of autolysis, which was also observed when the cells produced the secreted form of PI or a cell wall-anchored proteinase with PIII-type specificity. Autolysis was also increased when MG1363 expressed the cell wall-anchored hybrid PI/PIII-type proteinase PIac. Zymographic analysis of AcmA activity during stationary phase showed that AcmA was quickly degraded by PI and much more slowly by PrtP proteinases with PIII-type and intermediate specificities. Autolysis of L. lactis by AcmA was influenced by the specificity, amount, and location of the lactococcal proteinase. No autolysis was observed when the various proteinases were expressed in an L. lactis acmA deletion mutant, indicating that PrtP itself did not cause lysis of cells. The chain length of a strain was significantly shortened when the strain expressed a cell wall-anchored active proteinase.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.