Evidence map›Paper›PMID 9804712›Full record

Trial reportBMJ (Clinical research ed.)1998

Randomised controlled trial of effects of early discharge after surgery for breast cancer.

N Bundred, P Maguire, J Reynolds, J Grimshaw, J Morris, L Thomson, L Barr, A Baildam

Registry-linked trialOpen access · bronzeAbstract readClinical TrialRandomized Controlled Trial
In one paragraph

Trial report in BMJ (Clinical research ed.), 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03555227 (Ultrasound Guided), which is not on this map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03555227 nacompletednot on this mapstarted 2017, after this paper: background citation

Ultrasound Guided (USG) PECS Versus Local Infiltration Anaesthesia (LIA) for Breast Cancer Surgery - A Randomized Quadruple Blinded Efficacy and Safety Study

TypeinterventionalSponsorNational Health Service, United KingdomRan2017 to 2018Enrolled110ConditionsBreast Cancer FemaleArmsUSG PECS2 with Drug A (active), USG PECS2 with Drug P (placebo), Wound infiltration with Drug P (placebo), Wound infiltration with Drug A (active)
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Early discharge hospital at home.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Early discharge hospital at home.The Cochrane database of systematic reviews · 2009
    Pooled it
  4. Avoiding hospital admission through provision of hospital care at home: a systematic review and meta-analysis of individual patient data.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2009
    Pooled it
  5. Trial
  6. Trial
  7. Review
  8. Article
  9. Patients' perspective on day case breast surgery.Breast care (Basel, Switzerland) · 2015
    Article
  10. Article
  11. Article
  12. Efficacy of fibrin glue on seroma formation after breast surgery.International journal of breast cancer · 2012
    Article
  13. Article
  14. Article
  15. Article
  16. Risk factors for surgical site infection after major breast operation.Journal of the American College of Surgeons · 2008
    Article
  17. Article
  18. Article
  19. Postoperative education concerning the use of the upper limb, and exercise and treatment of the upper limb: cross-sectional survey of 105 breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2004
    Article
  20. The value of the Hospital Anxiety and Depression Scale (HADS) for comparing women with early onset breast cancer with population-based reference women.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2004
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

N BundredDepartment of Surgery, Christie Hospital NHS Trust, Manchester M20 4BX. bundredn@fs1.with.man.ac.uk
P Maguire
J Reynolds
J Grimshaw
J Morris
L Thomson
L Barr
A Baildam
The Christie Hospital · GBCancer Research UK · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the effect of early discharge from hospital after surgery for breast cancer on physical and psychological illness.

designRandomised controlled trial comparing discharge two days after surgery (before removal of drain) with standard management (discharge after removal of drain).

settingRegional breast unit. SUBJECTS: 100 women with early breast cancer undergoing mastectomy and axillary node clearance (20) or breast conservation surgery (80).

main outcome measuresPhysical illness (infection, seroma formation, shoulder movement) and psychological illness (checklist of concerns, Rotterdam symptom questionnaire, hospital anxiety and depression scale) preoperatively and at one month and three months postoperatively.

resultsWomen discharged early had greater shoulder movement (odds ratio 0.28 (95% confidence interval 0.08 to 0.95); P = 0.042) and less wound pain (odds ratio 0.28 (0.10 to 0.79); P = 0.016) three months after surgery compared with women given standard management. One month after surgery scores were significantly lower on the Rotterdam symptom questionnaire in patients who were discharged early (ratio of geometric mean scores 0.73 (0.55 to 0.98) P = 0.035), but rates of psychological illness generally did not differ between groups.

conclusionsIncreased rates of physical or psychological illness did not result from early discharge after surgery for breast cancer. This policy can be recommended for patients with support at home.

Indexed as

Length of StayAdultAgedAnxietyBreast NeoplasmsDepressionDrainageEdemaFemaleHumansInfectionsLymph Node ExcisionMastectomyMiddle AgedMusculoskeletal DiseasesPrognosis

Identifiers

PMID9804712
PMCPMC28705
OpenAlexW1985397122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.