ArticleThe Journal of experimental medicine1998
Characterization of gene expression in resting and activated mast cells.
Article in The Journal of experimental medicine, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 113 citations in OpenAlex.
- The Role of MIF and IL-10 as Molecular Yin-Yang in the Modulation of the Host Immune Microenvironment During Infections: African Trypanosome Infections as a Paradigm.Frontiers in immunology · 2022Review
- The role of macrophage migration inhibitory factor in mast cell-stimulated fibroblast proliferation and collagen production.PloS one · 2015Article
- Nutrition, immunological mechanisms and dietary immunomodulation in ADHD.European child & adolescent psychiatry · 2014Review
- Genome wide transcriptome analysis of dendritic cells identifies genes with altered expression in psoriasis.PloS one · 2013Article
- Errors in CGAP xProfiler and cDNA DGED: the importance of library parsing and gene selection algorithms.BMC bioinformatics · 2011Article
- Clustering-based approaches to SAGE data mining.BioData mining · 2008Article
- DiscoverySpace: an interactive data analysis application.Genome biology · 2007Article
- Identification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model.Arthritis research & therapy · 2006Article
- WEBSAGE: a web tool for visual analysis of differentially expressed human SAGE tags.Nucleic acids research · 2005Article
- Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach.BMC bioinformatics · 2005Article
- Overdispersed logistic regression for SAGE: modelling multiple groups and covariates.BMC bioinformatics · 2004Article
- Global gene expression profiling in interleukin-12-induced activation of CD8(+) cytotoxic T lymphocytes against mouse mammary Carcinoma.Cellular & molecular immunology · 2004Article
- Bayesian model accounting for within-class biological variability in Serial Analysis of Gene Expression (SAGE).BMC bioinformatics · 2004Article
- Vascular gene expression in nonneoplastic and malignant brain.The American journal of pathology · 2004Article
- Mouse testis transcriptome revealed using serial analysis of gene expression.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- Serial Analysis of Gene Expression: Applications in Malaria Parasite, Yeast, Plant, and Animal Studies.Journal of biomedicine & biotechnology · 2004Article
- MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues.Genome biology · 2003Article
- Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11.BMC immunology · 2002Article
- Unexpected signals in a system subject to kinetic proofreading.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- The mouse brain transcriptome by SAGE: differences in gene expression between P30 brains of the partial trisomy 16 mouse model of Down syndrome (Ts65Dn) and normals.Genome research · 2000Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To characterize gene expression in activated mast cells more comprehensively than heretofore, we surveyed the changes in genetic transcripts by the method of serial analysis of gene expression in the RBL-2H3 line of rat mast cells before and after they were stimulated through their receptors with high affinity for immunoglobulin E (FcepsilonRI). A total of 40,759 transcripts derived from 11,300 genes were analyzed. Among the diverse genes that had not been previously associated with mast cells and that were constitutively expressed were those for the cytokine macrophage migration inhibitory factor neurohormone receptors such as growth hormone- releasing factor and melatonin and components of the exocytotic machinery. In addition, several dozen transcripts were differentially expressed in response to antigen-induced clustering of the FcepsilonRI. Included among these were the genes for preprorelaxin, mitogen-activated protein kinase kinase 3, and the dual specificity protein phosphatase, rVH6. Significantly, the majority of genes differentially expressed in this well-studied model of mast cell activation have not been identified before this analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.