Evidence map›Paper›PMID 9799875›Full record

ArticleJournal of epidemiology and community health1998

Effects of changes in smoking status on risk estimates for myocardial infarction among women recruited for the Royal College of General Practitioners' Oral Contraception Study in the UK.

V Owen-Smith, P C Hannaford, M Warskyj, S Ferry, C R Kay

Abstract read
In one paragraph

Article in Journal of epidemiology and community health, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Smoking in young women in Scotland and future burden of hospital admission and death: a nested cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
    Article
  4. Impact of lifestyle in middle-aged women on mortality: evidence from the Royal College of General Practitioners' Oral Contraception Study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010
    Article
  5. Article
  6. Article
  7. Article
  8. Increased mortality among women with Rose angina who have not presented with ischaemic heart disease.The British journal of general practice : the journal of the Royal College of General Practitioners · 2003
    Article
  9. Pain and subsequent mortality and cancer among women in the Royal College of General Practitioners Oral Contraception Study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2003
    Article
  10. Stopping smoking and body weight in women living in the United Kingdom.The British journal of general practice : the journal of the Royal College of General Practitioners · 1999
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

V Owen-SmithRoyal College of General Practitioners' Manchester Research Unit.
P C Hannaford
M Warskyj
S Ferry
C R Kay

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectiveTo determine whether changes in smoking status among women recruited for the Royal College of General Practitioners' Oral Contraception Study affected previous risk estimates for myocardial infarction.

design(1) Postal survey between November 1994 and July 1995 of women still under general practitioner observation. Validation of the smoking information supplied by the women on the questionnaire by comparison with that reported by the general practitioner at recruitment to the main study. (2) Nested case-control study of 103 cases of myocardial infarction, matched with 309 controls, to see if different risk estimates were obtained when smoking status at recruitment or smoking status at time of event were used in the analysis.

setting650 general practices throughout the United Kingdom.

participants10,073 women who responded to the questionnaire (85.4% of 11,797 sent out). MAIN

resultsThere was good agreement between smoking information recorded by the general practitioner at recruitment and that supplied retrospectively by respondents to the questionnaire. The risk estimates for myocardial infarction associated with use of combined oral contraceptives (COCs) were almost identical irrespective of whether smoking status at recruitment or at time of event was used for the statistical adjustment. This was because few women stopped smoking while also using COCs. In fact, fewer regular smokers who have ever used COCs reported stopping smoking than never users. The risk estimates for myocardial infarction associated with smoking were smaller when smoking habits at recruitment was used than when smoking habits at time of event was used.

conclusionsPrevious results from the Oral Contraception Study regarding the effects of COCs are unlikely to have been biased by changes in the smoking habits of the cohort, but the effects of smoking have probably been underestimated. There is still a need for effective health education regarding the risks associated with smoking, particularly among users of COCs.

Indexed as

AdultBiasCase-Control StudiesContraceptives, Oral, CombinedFemaleHumansMiddle AgedMyocardial InfarctionRisk FactorsSensitivity and SpecificitySmokingSmoking CessationSurveys and QuestionnairesContraceptives, Oral, Combined

Identifiers

PMID9799875
PMCPMC1756732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.