ArticleGenetics1998
Novel mutations in the RAD3 and SSL1 genes perturb genome stability by stimulating recombination between short repeats in Saccharomyces cerevisiae.
Article in Genetics, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Mutations altering the DNA binding domains of the human RAD52 protein exert distinct effects on homologous recombination repair in Saccharomyces cerevisiae.G3 (Bethesda, Md.) · 2026Article
- Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination.Nucleic acids research · 2023Article
- Variants of the humanMicrobial cell (Graz, Austria) · 2020Article
- Constitutively active Artemis nuclease recognizes structures containing single-stranded DNA configurations.DNA repair · 2019Article
- Yeast-based assays for characterization of the functional effects of single nucleotide polymorphisms in human DNA repair genes.PloS one · 2018Article
- Growth Inhibition and DNA Damage Induced by X-Phenols in Yeast: A Quantitative Structure-Activity Relationship Study.ACS omega · 2017Article
- Crystal structure of the Rad3/XPD regulatory domain of Ssl1/p44.The Journal of biological chemistry · 2015Article
- Rad59 regulates association of Rad52 with DNA double-strand breaks.MicrobiologyOpen · 2012Article
- The SUMO isopeptidase Ulp2p is required to prevent recombination-induced chromosome segregation lethality following DNA replication stress.PLoS genetics · 2011Article
- RAD59 and RAD1 cooperate in translocation formation by single-strand annealing in Saccharomyces cerevisiae.Current genetics · 2010Article
- Msh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiae.PloS one · 2009Article
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- The DNA repair genes XPB and XPD defend cells from retroviral infection.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Multiple pathways promote short-sequence recombination in Saccharomyces cerevisiae.Molecular and cellular biology · 2002Article
- Nucleotide Excision Repair, Genome Stability, and Human Disease: New Insight from Model Systems.Journal of biomedicine & biotechnology · 2002Article
- Novel function of Rad27 (FEN-1) in restricting short-sequence recombination.Molecular and cellular biology · 2001Article
- Nucleotide excision repair/TFIIH helicases RAD3 and SSL2 inhibit short-sequence recombination and Ty1 retrotransposition by similar mechanisms.Molecular and cellular biology · 2000Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Maintaining genome stability requires that recombination between repetitive sequences be avoided. Because short, repetitive sequences are the most abundant, recombination between sequences that are below a certain length are selectively restricted. Novel alleles of the RAD3 and SSL1 genes, which code for components of a basal transcription and UV-damage-repair complex in Saccharomyces cerevisiae, have been found to stimulate recombination between short, repeated sequences. In double mutants, these effects are suppressed, indicating that the RAD3 and SSL1 gene products work together in influencing genome stability. Genetic analysis indicates that this function is independent of UV-damage repair and mutation avoidance, supporting the notion that RAD3 and SSL1 together play a novel role in the maintenance of genome integrity.
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