ArticleThe EMBO journal1998
The NMR structure of Escherichia coli ribosomal protein L25 shows homology to general stress proteins and glutaminyl-tRNA synthetases.
Article in The EMBO journal, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 73 citations in OpenAlex.
- Molecular dynamics of three different α-helices in ribosomal protein L25 fromBiochemistry and biophysics reports · 2024Article
- Sampling Native-like Structures of RNA-Protein Complexes through Rosetta Folding and Docking.Structure (London, England : 1993) · 2019Article
- Adenine protonation enables cyclic-di-GMP binding to cyclic-GAMP sensing riboswitches.RNA (New York, N.Y.) · 2018Article
- Evaluation ofJournal of biomolecular NMR · 2017Article
- Ligand binding to 2΄-deoxyguanosine sensing riboswitch in metabolic context.Nucleic acids research · 2017Article
- Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy.Nucleic acids research · 2017Article
- Impact of spin label rigidity on extent and accuracy of distance information from PRE data.Journal of biomolecular NMR · 2017Article
- The role of structural bioinformatics resources in the era of integrative structural biology.Acta crystallographica. Section D, Biological crystallography · 2013Article
- The natural history of ubiquitin and ubiquitin-related domains.Frontiers in bioscience (Landmark edition) · 2012Review
- Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy.Nucleic acids research · 2011Article
- 13C-direct detected NMR experiments for the sequential J-based resonance assignment of RNA oligonucleotides.Journal of biomolecular NMR · 2010Article
- Small but versatile: the extraordinary functional and structural diversity of the beta-grasp fold.Biology direct · 2007Article
- Identification of Borrelia burgdorferi ribosomal protein L25 by the phage surface display method and evaluation of the protein's value for serodiagnosis.Journal of clinical microbiology · 2006Article
- Comparison of different torsion angle approaches for NMR structure determination.Journal of biomolecular NMR · 2006Article
- An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Long-residency hydration, cation binding, and dynamics of loop E/helix IV rRNA-L25 protein complex.Biophysical journal · 2004Article
- Triple resonance experiments for the simultaneous correlation of H6/H5 and exchangeable protons of pyrimidine nucleotides in 13C,15N-labeled RNA applicable to larger RNA molecules.Journal of biomolecular NMR · 2003Article
- 5 S rRNA: structure and interactions.The Biochemical journal · 2003Review
- Role of ctc from Listeria monocytogenes in osmotolerance.Applied and environmental microbiology · 2003Article
- Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C.RNA (New York, N.Y.) · 2002Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The structure of the Escherichia coli ribosomal protein L25 has been determined to an r.m.s. displacement of backbone heavy atoms of 0.62 +/- 0.14 A by multi-dimensional heteronuclear NMR spectroscopy on protein samples uniformly labeled with 15N or 15N/13C. L25 shows a new topology for RNA-binding proteins consisting of a six-stranded beta-barrel and two alpha-helices. A putative RNA-binding surface for L25 has been obtained by comparison of backbone 15N chemical shifts for L25 with and without a bound cognate RNA containing the eubacterial E-loop that is the site for binding of L25 to 5S ribosomal RNA. Sequence comparisons with related proteins, including the general stress protein, CTC, show that the residues involved in RNA binding are highly conserved, thereby providing further confirmation of the binding surface. Tertiary structure comparisons indicate that the six-stranded beta-barrels of L25 and of the tRNA anticodon-binding domain of glutaminyl-tRNA synthetase are similar.
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